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NTF4 recombinant protein

Scan QR to view Datasheet Catalog #    MBS204641
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NTF4, Recombinant Protein

 Also Known As   

NTF4, 81-210aa, Human, E Coli (Denatured)

 Product Synonym Names    Neurotrophin-4; NT4; NT5; NTF5; NT-4/5
 Product Gene Name   

NTF4 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGVSETAPAS RRGELAVCDA VSGWVTDRRT AVDLRGREVE VLGEVPAAGG SPLRQYFFET RCKADNAEEG GPGAGGGGCR GVDRRHWVSE CKAKQSYVRA LTADAQGRVG WRWIRIDTAC VCTLLSRTGR A
 OMIM    M86528 Genomic DNA
 3D Structure    ModBase 3D Structure for P34130
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 Host    E Coli
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 Purity/Purification    > 85% by SDS-PAGE
 Form/Format    Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.4M urea, 20% glycerol
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of NTF4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for NTF4 recombinant protein

   NTF4, also known as neurotrophin 4, is a member of a family of neurotrophic factors neurotrophins that control survival and differentiation of mammalian neurons. This protein is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derivedneurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF4-deficient mice only show minor cellular deficits and develop normally to adulthood.
 Product Categories/Family for NTF4 recombinant protein    Neuroscience
 Applications Tested/Suitable for NTF4 recombinant protein   

SDS-PAGE

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 SDS-Page of NTF4 recombinant protein    NTF4 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for NTF4. It may not necessarily be applicable to this product.
 NCBI GI #    5453808
 NCBI GeneID    4909
 NCBI Accession #    NP_006170 [Other Products]
 NCBI GenBank Nucleotide #    NM_006179.4 [Other Products]
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 UniProt Primary Accession #    P34130 [Other Products]
 UniProt Secondary Accession #    Q6FH56 [Other Products]
 UniProt Related Accession #    P34130 [Other Products]
 Molecular Weight    14.1 kDa (131aa)
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 NCBI Official Full Name    neurotrophin-4 preproprotein
 NCBI Official Synonym Full Names    neurotrophin 4
 NCBI Official Symbol    NTF4 [Similar Products]
 NCBI Official Synonym Symbols   
NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5
[Similar Products]
 NCBI Protein Information    neurotrophin-4
 UniProt Protein Name    Neurotrophin-4
 UniProt Synonym Protein Names   
Neurotrophin-5; NT-5; Neutrophic factor 4
 Protein Family    Neurotrophin
 UniProt Gene Name    NTF4 [Similar Products]
 UniProt Synonym Gene Names    NTF5; NT-4; NT-5 [Similar Products]
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 NCBI Summary for NTF4    This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NTF4    Target-derived survival factor for peripheral sensory sympathetic neurons.
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Product References and Citations for NTF4 recombinant protein

   Pasutto F., et al. (2009) Am. J. Hum. Genet. 85:447-456.; Liu Y., et al. (2010) Am. J. Hum. Genet. 86:498-499.
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 Research Articles on NTF4    1. Meta-analysis found the levels of both NT-3 and NT-4/5 were significantly increased in bipolar disorder patients. Through subgroup analysis, this increase persisted only in patients in depressed state, but not in manic or euthymic state. In addition, we found the differences in NT-3 and NT-4/5 were significantly associated with the duration of illness, but not by the mean age or female proportion.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NTF4 recombinant proteinPathways associated with NTF4 recombinant protein
 Reference Product  PubMed Publications
 NTF3 recombinant protein  >10 publications with NTF4 and NTF3
 GDNF recombinant protein  >5 publications with NTF4 and GDNF
 NTRK1 recombinant protein  >4 publications with NTF4 and NTRK1
 CNTF recombinant protein  >3 publications with NTF4 and CNTF
 NGFR recombinant protein  >3 publications with NTF4 and NGFR
 NTRK2 recombinant protein  >3 publications with NTF4 and NTRK2
 NTRK3 recombinant protein  >2 publications with NTF4 and NTRK3
 Products by Pathway  Pathway Diagram
 Differentiation Pathway antibodies  Differentiation Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Neurotrophic Factor-mediated Trk Receptor Signaling Pathway antibodies  Neurotrophic Factor-mediated Trk Receptor Signaling Pathway Diagram
 Neurotrophin Signaling Pathway antibodies  Neurotrophin Signaling Pathway Diagram
 Neurotrophin Signaling Pathway antibodies  Neurotrophin Signaling Pathway Diagram
 P75(NTR)-mediated Signaling Pathway antibodies  P75(NTR)-mediated Signaling Pathway Diagram
Diseases associated with NTF4 recombinant proteinOrgans/Tissues associated with NTF4 recombinant protein
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >2 publications with NTF4 and Disease Models, Animal
 Nervous System Diseases Antibodies  >2 publications with NTF4 and Nervous System Diseases
 Nerve Degeneration Antibodies  >2 publications with NTF4 and Nerve Degeneration
 Immune System Diseases Antibodies  >1 publications with NTF4 and Immune System Diseases
 Optic Nerve Diseases Antibodies  >1 publications with NTF4 and Optic Nerve Diseases
 Hypertension Antibodies  >1 publications with NTF4 and Hypertension
 Breast Neoplasms Antibodies  >1 publications with NTF4 and Breast Neoplasms
 Memory Disorders Antibodies  >1 publications with NTF4 and Memory Disorders
 Learning Disorders Antibodies  >1 publications with NTF4 and Learning Disorders
 Lung Diseases Antibodies  >1 publications with NTF4 and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >2 publications with NTF4 and Ovary
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