NP_037383
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
tachykinin-3 isoform 1 preproprotein
NCBI Official Synonym Full Names
tachykinin 3
NCBI Official Synonym Symbols
NKB; HH10; NKNB; PRO1155; ZNEUROK1 [Similar Products]
NCBI Protein Information
tachykinin-3
UniProt Protein Name
Tachykinin-3
UniProt Synonym Protein Names
ZNEUROK1
UniProt Synonym Gene Names
NCBI Summary for TAC3
This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded preproprotein is proteolytically processed to generate the mature peptide, which is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. This peptide is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
UniProt Comments for TAC3
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles (). Is a critical central regulator of gonadal function.
Product References and Citations for TAC3 recombinant protein
Topaloglu AK., et al. (2009). Nat Genet. 41 (3):354-8; Rance NE., et al. (2009). Peptides. 30 (1):111-22.;
Research Articles on TAC3
Precautions
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Products associated with TAC3 recombinant protein
Pathways associated with TAC3 recombinant protein
Diseases associated with TAC3 recombinant protein
Organs/Tissues associated with TAC3 recombinant protein
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