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ENO2 recombinant protein :: Neuronal Specific Enolase Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS142439 ENO2 recombinant protein
Unit / Price
0.002 mg  /  $140 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $4,995 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Neuronal Specific Enolase (ENO2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Neuronal Specific Enolase, His Tag

 Product Synonym Names    ENO2 Human, His; Neuron Specific Enolase Human Recombinant, His Tag; Gamma-enolase; EC 4.2.1.11; 2-phospho-D-glycerate hydro-lyase; Neural enolase; Neuron-specific enolase; NSE; Enolase 2; ENO2; ENO2, His
 Product Gene Name   

ENO2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    131360
 3D Structure    ModBase 3D Structure for P09104
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 Host    E Coli
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 Purity/Purification    Greater than 95% as determined by SDS-PAGE. Single band on Western Blot.
 Form/Format    Enolase 2 is supplied in 10mM Tris-HCl (pH 8), 250mM NaCl, 0.5mM DTT, 1.5mM Cysteine, and 50% Glycerol.
Sterile Filtered clear solution.
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 Preparation and Storage    Store at 4 degree C if entire vial will be used within 1-2 weeks. Store, frozen at -20 degree C for longer periods of time. Please prevent freeze-thaw cycles.
 Other Notes    Small volumes of ENO2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for ENO2 recombinant protein

   Description: Neuron Specific Enolase Human Recombinant is expressed in E Coli containing 433 amino acids 2-434 fused to an amino terminal hexahistidine tag.The NSE is purified by proprietary chromatographic techniques.

Introduction: NSE is the ?? isoform of the glycolytic enzyme enolase and is expressed primarily in neurons, in normal and neoplastic neuroendocrine cells. NSE is a highly soluble cytoplasmic protein that is readily secreted into the CSF and serum following tissue damage. NSE shows neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons and binds in a calcium-dependent manner to cultured neocortical neurons promoting cell survival.
 Product Categories/Family for ENO2 recombinant protein    ENZYMES; Enzymes; Enolase
NCBI/Uniprot data below describe general gene information for ENO2. It may not necessarily be applicable to this product.
 NCBI GI #    5803011
 NCBI GeneID    2026
 NCBI Accession #    NP_001966.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001975.2 [Other Products]
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 UniProt Primary Accession #    P09104 [Other Products]
 UniProt Secondary Accession #    Q96J33; B7Z2X9 [Other Products]
 UniProt Related Accession #    P09104 [Other Products]
 Molecular Weight    42,707 Da
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 NCBI Official Full Name    gamma-enolase
 NCBI Official Synonym Full Names    enolase 2 (gamma, neuronal)
 NCBI Official Symbol    ENO2 [Similar Products]
 NCBI Official Synonym Symbols   
NSE; HEL-S-279
[Similar Products]
 NCBI Protein Information    gamma-enolase; 2-phospho-D-glycerate hydro-lyase; 2-phospho-D-glycerate hydrolyase; epididymis secretory protein Li 279; neural enolase; neuron specific gamma enolase; neuron-specific enolase; neurone-specific enolase
 UniProt Protein Name    Gamma-enolase
 UniProt Synonym Protein Names   
2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; Neuron-specific enolase; NSE
 Protein Family    Enolase
 UniProt Gene Name    ENO2 [Similar Products]
 UniProt Synonym Gene Names    NSE [Similar Products]
 UniProt Entry Name    ENOG_HUMAN
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 NCBI Summary for ENO2    This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ENO2    ENO2: an enzyme with 2-phospho-D-glycerate hydro-lyase activity. One of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.

Protein type: Lyase; EC 4.2.1.11; Carbohydrate Metabolism - glycolysis and gluconeogenesis

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: extracellular space; phosphopyruvate hydratase complex; photoreceptor inner segment; plasma membrane; perikaryon; cytosol

Molecular Function: magnesium ion binding; phosphopyruvate hydratase activity

Biological Process: glycolysis; carbohydrate metabolic process; glucose metabolic process; pathogenesis; gluconeogenesis
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 Research Articles on ENO2    1. This is the first study to suggest blood NFL mRNA as a surrogate marker for early prediction of prediabetic peripheral neuropathy, while NSE mRNA levels may be of no diagnostic value in prediabetic patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ENO2 recombinant proteinPathways associated with ENO2 recombinant protein
 Reference Product  PubMed Publications
 ALDOC recombinant protein  >3 publications with ENO2 and ALDOC
 PCK1 recombinant protein  >3 publications with ENO2 and PCK1
 GPI recombinant protein  >2 publications with ENO2 and GPI
 PKM2 recombinant protein  >2 publications with ENO2 and PKM2
 ALDOA recombinant protein  >1 publications with ENO2 and ALDOA
 PKLR recombinant protein  >1 publications with ENO2 and PKLR
 Products by Pathway  Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Gluconeogenesis Pathway antibodies  Gluconeogenesis Pathway Diagram
 Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies  Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram
 Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies  Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram
 Glucose Metabolism Pathway antibodies  Glucose Metabolism Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
Diseases associated with ENO2 recombinant proteinOrgans/Tissues associated with ENO2 recombinant protein
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >8 publications with ENO2 and Disease Models, Animal
 Nervous System Diseases Antibodies  >7 publications with ENO2 and Nervous System Diseases
 Brain Diseases Antibodies  >5 publications with ENO2 and Brain Diseases
 Adenocarcinoma Antibodies  >4 publications with ENO2 and Adenocarcinoma
 Kidney Diseases Antibodies  >3 publications with ENO2 and Kidney Diseases
 Inflammation Antibodies  >2 publications with ENO2 and Inflammation
 Prostatic Neoplasms Antibodies  >2 publications with ENO2 and Prostatic Neoplasms
 Hypertension Antibodies  >2 publications with ENO2 and Hypertension
 Lung Diseases Antibodies  >2 publications with ENO2 and Lung Diseases
 Neoplasms, Experimental Antibodies  >2 publications with ENO2 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >17 publications with ENO2 and Brain
 Blood Antibodies  >10 publications with ENO2 and Blood
 Muscle Antibodies  >8 publications with ENO2 and Muscle
 Skin Antibodies  >4 publications with ENO2 and Skin
 Intestine Antibodies  >4 publications with ENO2 and Intestine
 Vascular Antibodies  >4 publications with ENO2 and Vascular
 Lung Antibodies  >4 publications with ENO2 and Lung
 Kidney Antibodies  >4 publications with ENO2 and Kidney
 Bone Antibodies  >4 publications with ENO2 and Bone
 Testis Antibodies  >3 publications with ENO2 and Testis
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