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Gpm6a recombinant protein :: Neuronal membrane glycoprotein M6-a (Gpm6a) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS948745 Gpm6a recombinant protein
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 Product Name   

Neuronal membrane glycoprotein M6-a (Gpm6a), Recombinant Protein

 Also Known As   

Recombinant Mouse Neuronal membrane glycoprotein M6-a (Gpm6a)

 Product Synonym Names    Recombinant Neuronal membrane glycoprotein M6-a (Gpm6a); Neuronal membrane glycoprotein M6-a; M6a
 Product Gene Name   

Gpm6a recombinant protein

[Similar Products]
 Product Synonym Gene Name    Gpm6a; M6a [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-278
 Chromosome Location    Chromosome: 8; NC_000074.6 (54779434..55060878). Location: 8 B3.2; 8
 3D Structure    ModBase 3D Structure for P35802
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Gpm6a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Gpm6a. It may not necessarily be applicable to this product.
 NCBI GI #    359279948
 NCBI GeneID    234267
 NCBI Accession #    NP_001240683.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001253754.1 [Other Products]
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 UniProt Primary Accession #    P35802 [Other Products]
 UniProt Related Accession #    P35802 [Other Products]
 Molecular Weight    31,149 Da [Similar Products]
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 NCBI Official Full Name    neuronal membrane glycoprotein M6-a isoform 2
 NCBI Official Synonym Full Names    glycoprotein m6a
 NCBI Official Symbol    Gpm6a [Similar Products]
 NCBI Official Synonym Symbols   
M6A; Gpm6
[Similar Products]
 NCBI Protein Information    neuronal membrane glycoprotein M6-a
 UniProt Protein Name    Neuronal membrane glycoprotein M6-a
 Protein Family    Neuronal membrane glycoprotein
 UniProt Gene Name    Gpm6a [Similar Products]
 UniProt Synonym Gene Names    M6a; M6a [Similar Products]
 UniProt Entry Name    GPM6A_MOUSE
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 UniProt Comments for Gpm6a    GPM6A: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. Belongs to the myelin proteolipid protein family.

Protein type: Membrane protein, integral; Cell surface; Membrane protein, multi-pass; Channel, calcium

Cellular Component: neuron projection; cell projection; cell soma; membrane; plasma membrane; integral to membrane; vesicle; filopodium

Molecular Function: calcium channel activity

Biological Process: positive regulation of filopodium formation; nervous system development; synaptogenesis; neuron migration; stem cell differentiation; neurite morphogenesis
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 Research Articles on Gpm6a    1. analysis of actin-independent behavior and membrane deformation exhibited by the four-transmembrane protein M6a
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with Gpm6a recombinant proteinOrgans/Tissues associated with Gpm6a recombinant protein
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >3 publications with Gpm6a and Disease Models, Animal
 Nervous System Diseases Antibodies  >2 publications with Gpm6a and Nervous System Diseases
 Atrophy Antibodies  >1 publications with Gpm6a and Atrophy
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >16 publications with Gpm6a and Brain
 Embryonic Tissue Antibodies  >4 publications with Gpm6a and Embryonic Tissue
 Kidney Antibodies  >2 publications with Gpm6a and Kidney
 Eye Antibodies  >2 publications with Gpm6a and Eye
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