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DEFA3 recombinant protein :: Neutrophil defensin 3 (DEFA3) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS955711
SDS-PAGE
Unit / Price
0.05 mg (E-Coli)  /  $445 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $590 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $625 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $650 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $785 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $845 +1 FREE 8GB USB
1 mg (E-Coli)  /  $920 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $955 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $995 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,025 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,435 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,440 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,565 +1 FREE 8GB USB
1 mg (Baculovirus)  /  $1,930 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Neutrophil defensin 3 (DEFA3), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Neutrophil defensin 3 (DEFA3)

 Product Gene Name   

DEFA3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    39-94. Full length of mature protein
 Sequence    DIPEVVVSLA WDESLAPKHP GSRKNMDCYC RIPACIAGER RYGTCIYQGR LWAFCC
 OMIM    604522
 3D Structure    ModBase 3D Structure for P59666
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of DEFA3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for DEFA3 recombinant protein

   Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. This protein, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from defensin, alpha 1 by only one amino acid.
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 SDS-PAGE of DEFA3 recombinant protein    DEFA3 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for DEFA3. It may not necessarily be applicable to this product.
 NCBI GI #    4885179
 NCBI GeneID    1668
 NCBI Accession #    NP_005208.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005217.3 [Other Products]
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 UniProt Primary Accession #    P59666 [Other Products]
 UniProt Secondary Accession #    P11479; Q14125 [Other Products]
 UniProt Related Accession #    P59666 [Other Products]
 Molecular Weight    10,245 Da
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 NCBI Official Full Name    neutrophil defensin 3 preproprotein
 NCBI Official Synonym Full Names    defensin alpha 3
 NCBI Official Symbol    DEFA3 [Similar Products]
 NCBI Official Synonym Symbols   
HP3; DEF3; HNP3; HP-3; HNP-3
[Similar Products]
 NCBI Protein Information    neutrophil defensin 3
 UniProt Protein Name    Neutrophil defensin 3
 UniProt Synonym Protein Names   
Defensin, alpha 3; HNP-3; HP-3; HP3
 Protein Family    Neutrophil defensin
 UniProt Gene Name    DEFA3 [Similar Products]
 UniProt Synonym Gene Names    DEF3; HP-3; HP3; HP-2; HP2 [Similar Products]
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 NCBI Summary for DEFA3    Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation. [provided by RefSeq, Oct 2014]
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 UniProt Comments for DEFA3    Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
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 Research Articles on DEFA3    1. DEFA1, DEFA3, and PPBP expression was significantly increased in hyperlipidemia and coronary heart disease patients compared with controls.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DEFA3 recombinant proteinPathways associated with DEFA3 recombinant protein
 Reference Product  PubMed Publications
 DEFA1 recombinant protein  >15 publications with DEFA3 and DEFA1
 DEFA4 recombinant protein  >3 publications with DEFA3 and DEFA4
 DEFB1 recombinant protein  >2 publications with DEFA3 and DEFB1
 CAMP recombinant protein  >1 publications with DEFA3 and CAMP
 DEFA5 recombinant protein  >1 publications with DEFA3 and DEFA5
 DEFA6 recombinant protein  >1 publications with DEFA3 and DEFA6
 Products by Pathway  Pathway Diagram
 Alpha-defensins Pathway antibodies  Alpha-defensins Pathway Diagram
 Antimicrobial Peptides Pathway antibodies  Antimicrobial Peptides Pathway Diagram
 Defensins Pathway antibodies  Defensins Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
Diseases associated with DEFA3 recombinant proteinOrgans/Tissues associated with DEFA3 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7 publications with DEFA3 and Inflammation
 Nervous System Diseases Antibodies  >2 publications with DEFA3 and Nervous System Diseases
 Skin Diseases Antibodies  >1 publications with DEFA3 and Skin Diseases
 Glioma Antibodies  >1 publications with DEFA3 and Glioma
 Necrosis Antibodies  >1 publications with DEFA3 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >16 publications with DEFA3 and Blood
 Connective Tissue Antibodies  >1 publications with DEFA3 and Connective Tissue
 Kidney Antibodies  >1 publications with DEFA3 and Kidney
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