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NuDT9 recombinant protein

Scan QR to view Datasheet Catalog #    MBS204059
SDS-PAGE
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NuDT9, Recombinant Protein

 Also Known As   

NuDT9, 47-350aa, Human, His tag, E Coli

 Product Synonym Names    ADP-ribose pyrophosphatase; mitochondrial isoform a; MGC3037; NuDT10
 Product Gene Name   

NuDT9 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MNTNVMSGSN GSKENSHNKA RTSPYPGSKV ERSQVPNEKV GWLVEWQDYK PVEYTAVSVL AGPRWADPQI SESNFSPKFN EKDGHVERKS KNGLYEIENG RPRNPAGRTG LVGRGLLGRW GPNHAADPII TRWKRDSSGN KIMHPVSGKH ILQFVAIKRK DCGEWAIPGG MVDPGEKISA TLKREFGEEA LNSLQKTSAE KREIEEKLHK LFSQDHLVIY KGYVDDPRNT DNAWMETEAV NYHDETGEIM DNLMLEAGDD AGKVKWVDIN DKLKLYASHS QFIKLVAEKR DAHWSEDSEA DCHAL
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 Purity/Purification    > 95 % by SDS - PAGE
 Form/Format    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag    His-tag
 Expression System    E Coli
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of NuDT9 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for NuDT9 recombinant protein

   NuDT9 belongs to a superfamily of Nudix hydrolases. It is known to function as a highly specific adenosine diphosphate ribose pyrophosphatase that hydrolyzes ADP ribose to AMP and ribose 5'-phosphate. It has been suggested that NuDT9 may be involved in the regulation of the menstrual cycle and may be related to the proliferation of glandular cells in the human endometrium. Recombinant human NuDT9 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
 Product Categories/Family for NuDT9 recombinant protein    Signal Transduction
 Applications Tested/Suitable for NuDT9 recombinant protein   

SDS-PAGE

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 SDS-PAGE of NuDT9 recombinant protein    NuDT9 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for NuDT9. It may not necessarily be applicable to this product.
 NCBI GI #    13129010
 NCBI GeneID    53343
 NCBI Accession #    NP_076952 [Other Products]
 NCBI GenBank Nucleotide #    NM_024047.4 [Other Products]
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 UniProt Secondary Accession #    Q8NBN1; Q8NCB9; Q8NG25 [Other Products]
 UniProt Related Accession #    Q9BW91 [Other Products]
 Molecular Weight    36.5 kDa (325aa), confirmed by MALDI-TOF (molecular weight on SDS-PAGE will appear higher)
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 NCBI Official Full Name    ADP-ribose pyrophosphatase, mitochondrial isoform a
 NCBI Official Synonym Full Names    nudix (nucleoside diphosphate linked moiety X)-type motif 9
 NCBI Official Symbol    NUDT9 [Similar Products]
 NCBI Official Synonym Symbols   
NUDT10
[Similar Products]
 NCBI Protein Information    ADP-ribose pyrophosphatase, mitochondrial; ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ADP-ribose pyrosphosphatase NUDT9; ADPR-PPase; adenosine diphosphoribose pyrophosphatase; nucleoside diphosphate linked moiety X-type motif 9
 UniProt Protein Name    ADP-ribose pyrophosphatase, mitochondrial
 UniProt Synonym Protein Names   
ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase; Nucleoside diphosphate-linked moiety X motif 9; Nudix motif 9
 Protein Family    Nudix hydrolase
 UniProt Gene Name    NUDT9 [Similar Products]
 UniProt Synonym Gene Names    NUDT10; ADPR-PPase; Nudix motif 9 [Similar Products]
 UniProt Entry Name    NUDT9_HUMAN
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 NCBI Summary for NuDT9    The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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 UniProt Comments for NuDT9    NUDT9: Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'- phosphate. Belongs to the Nudix hydrolase family. NudF subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.1.13; Nucleotide Metabolism - purine; Hydrolase; Mitochondrial

Chromosomal Location of Human Ortholog: 4q22.1

Cellular Component: mitochondrial matrix; intracellular

Molecular Function: ADP-ribose diphosphatase activity; ADP-sugar diphosphatase activity; adenosine-diphosphatase activity

Biological Process: nucleobase, nucleoside and nucleotide metabolic process; ADP catabolic process; IDP catabolic process
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Product References and Citations for NuDT9 recombinant protein

   Perraud AL., et al. (2001) Nature. 411(6837):595-9.
Perraud AL., et al. (2003) J Biol Chem. 278(3):1794-801.
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 Research Articles on NuDT9    1. NUDT9 may be involved in the regulation of the menstrual cycle and may be related to the proliferation of glandular cells in the human endometrium
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NuDT9 recombinant proteinPathways associated with NuDT9 recombinant protein
 Reference Product  PubMed Publications
 NUDT5 recombinant protein  >2 publications with NuDT9 and NUDT5
 GLOD4 recombinant protein  >1 publications with NuDT9 and GLOD4
 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Phosphate Bond Hydrolysis By NUDT Proteins Pathway antibodies  Phosphate Bond Hydrolysis By NUDT Proteins Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
Diseases associated with NuDT9 recombinant proteinOrgans/Tissues associated with NuDT9 recombinant protein
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >1 publications with NuDT9 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with NuDT9 and Liver
 Uterus Antibodies  >1 publications with NuDT9 and Uterus
 Muscle Antibodies  >1 publications with NuDT9 and Muscle
 Heart Antibodies  >1 publications with NuDT9 and Heart
 Pancreas Antibodies  >1 publications with NuDT9 and Pancreas
 Placenta Antibodies  >1 publications with NuDT9 and Placenta
 Embryonic Tissue Antibodies  >1 publications with NuDT9 and Embryonic Tissue
 Kidney Antibodies  >1 publications with NuDT9 and Kidney
 Brain Antibodies  >1 publications with NuDT9 and Brain
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