P16791.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
NCBI Official Full Name
Nuclear egress membrane protein
UniProt Protein Name
Nuclear egress membrane protein
UniProt Synonym Protein Names
Primary envelopment factor UL50; Protein HFLF4
UniProt Entry Name
UL50_HCMVA
UniProt Comments for UL50
Function: Plays a major role in virion nuclear egress, the first step of virion release from infected cell. Viral capsids are initially assembled within the nucleus, UL53/UL50 complex induces capsids budding and envelopment into the perinuclear space. Then UL53/UL50 complex promotes fusion of perinuclear virion envelope with the outer nuclear membrane, releasing viral capsid into the cytoplasm where it will engages budding sites in the Golgi or trans-Golgi network
By similarity.
Subunit structure: Forms a complex with UL50
By similarity.
Subcellular location: Host nucleus inner membrane; Single-pass membrane protein. Note: Localizes also at the transient membrane of perinuclear virions
By similarity.
Sequence similarities: Belongs to the herpesviridae UL34 family.
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Products associated with UL50 recombinant protein
Pathways associated with UL50 recombinant protein
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