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Rorb recombinant protein :: Nuclear receptor ROR-beta (Rorb) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS959495 Rorb recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $890 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,105 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,190 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,315 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,315 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,355 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,400 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,490 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,865 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,010 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,045 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,265 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,640 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Nuclear receptor ROR-beta (Rorb), Recombinant Protein

 Also Known As   

Recombinant Rat Nuclear receptor ROR-beta (Rorb)

 Product Gene Name   

Rorb recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-470aa, Full length protein
 Sequence    MCENQLKTKA DGTAQIEVIP CKICGDKSSG IHYGVITCEG CKGFFRRSQQ NNASYSCPRQ RNCLIDRTNR NRCQHCRLQK CLALGMSRDA VKFGRMSKKQ RDSLYAEVQK HQQRLQEQRQ QQSGEAEALA RVYSSSISNG LSNLNTETGG TYANGHVIDL PKSEGYYNID SGQPSPDQSG LDMTGIKQIK QEPIYDLTSV HNLFTYSSFN NGQLAPGITM SEIDRIAQNI IKSHLETCQY TMEELHQLAW QTHTYEEIKA YQSKSREALW QQCAIQITHA IQYVVEFAKR ITGFMELCQN DQILLLKSGC LEVVLVRMCR AFNPLNNTVL FEGKYGGMQM FKALGSDDLV NEAFDFAKNL CSLQLTEEEI ALFSSAVLIS PDRAWLLEPR KVQKLQEKIY FALQHVIQKN HLDDETLAKL IAKIPTITAV CNLHGEKLQV FKQSHPDIVN TLFPPLYKEL FNPDCAAVCK
 3D Structure    ModBase 3D Structure for P45446
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Rorb recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Rorb recombinant protein

   This protein is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation.
NCBI/Uniprot data below describe general gene information for Rorb. It may not necessarily be applicable to this product.
 NCBI GI #    124028632
 NCBI GeneID    309288
 NCBI Accession #    P45446.3 [Other Products]
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 UniProt Primary Accession #    P45446 [Other Products]
 UniProt Related Accession #    P45446 [Other Products]
 Molecular Weight    52,068 Da
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 NCBI Official Full Name    Nuclear receptor ROR-beta
 NCBI Official Synonym Full Names    RAR-related orphan receptor B
 NCBI Official Symbol    Rorb [Similar Products]
 NCBI Protein Information    nuclear receptor ROR-beta
 UniProt Protein Name    Nuclear receptor ROR-beta
 UniProt Synonym Protein Names   
Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; Retinoid-related orphan receptor-beta
 Protein Family    Nuclear receptor
 UniProt Gene Name    Rorb [Similar Products]
 UniProt Synonym Gene Names    Nr1f2; Rzrb [Similar Products]
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 NCBI Summary for Rorb    The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]
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 UniProt Comments for Rorb    Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity.
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 Research Articles on Rorb    1. RORbeta, ER81 and Nurr1 are expressed in rat neocortex
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Rorb recombinant proteinPathways associated with Rorb recombinant protein
 Reference Product  PubMed Publications
 Nr4a2 recombinant protein  >3 publications with Rorb and Nr4a2
 Nr1d1 recombinant protein  >2 publications with Rorb and Nr1d1
 Products by Pathway  Pathway Diagram
 Circadian Rhythm - Mammal Pathway antibodies  Circadian Rhythm - Mammal Pathway Diagram
 Circadian Rhythm - Mammal Pathway antibodies  Circadian Rhythm - Mammal Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Nuclear Receptor Transcription Pathway antibodies  Nuclear Receptor Transcription Pathway Diagram
Organs/Tissues associated with Rorb recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >15 publications with Rorb and Brain
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