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YBX1 recombinant protein :: Nuclease-sensitive element-binding protein 1 (YBX1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS958394 YBX1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $730 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $985 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $990 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,075 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,145 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,235 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,255 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,300 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,530 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,805 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,875 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,970 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,400 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Nuclease-sensitive element-binding protein 1 (YBX1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Nuclease-sensitive element-binding protein 1 (YBX1)

 Product Gene Name   

YBX1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS958394 COA    COA PDF
 Sequence Positions    2-324\naa, Full Length of Mature Protein
 Sequence    SSEAETQQPP AAPPAAPALS AADTKPGTTG SGAGSGGPGG LTSAAPAGGD KKVIATKVLG TVKWFNVRNG YGFINRNDTK EDVFVHQTAI KKNNPRKYLR SVGDGETVEF DVVEGEKGAE AANVTGPGGV PVQGSKYAAD RNHYRRYPRR RGPPRNYQQN YQNSESGEKN EGSESAPEGQ AQQRRPYRRR RFPPYYMRRP YGRRPQYSNP PVQGEVMEGA DNQGAGEQGR PVRQNMYRGY RPRFRRGPPR QRQPREDGNE EDKENQGDET QGQQPPQRRY RRNFNYRRRR PENPKPQDGK ETKAADPPAE NSSAPEAEQG GAE
 OMIM    154030
 3D Structure    ModBase 3D Structure for P67809
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of YBX1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for YBX1. It may not necessarily be applicable to this product.
 NCBI GI #    34098946
 NCBI GeneID    4904
 NCBI Accession #    NP_004550.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004559.4 [Other Products]
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 UniProt Primary Accession #    P67809 [Other Products]
 UniProt Secondary Accession #    P16990; P16991; Q14972; Q15325; Q5FVF0 [Other Products]
 UniProt Related Accession #    P67809 [Other Products]
 Molecular Weight    35,924 Da
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 NCBI Official Full Name    nuclease-sensitive element-binding protein 1
 NCBI Official Synonym Full Names    Y-box binding protein 1
 NCBI Official Symbol    YBX1 [Similar Products]
 NCBI Official Synonym Symbols   
YB1; BP-8; CSDB; DBPB; YB-1; CBF-A; CSDA2; EFI-A; NSEP1; NSEP-1; MDR-NF1
[Similar Products]
 NCBI Protein Information    nuclease-sensitive element-binding protein 1
 UniProt Protein Name    Nuclease-sensitive element-binding protein 1
 UniProt Synonym Protein Names   
CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Y-box transcription factor; Y-box-binding protein 1; YB-1
 Protein Family    Nuclease-sensitive element-binding protein
 UniProt Gene Name    YBX1 [Similar Products]
 UniProt Synonym Gene Names    NSEP1; YB1; CBF-A; DBPB; EFI-A; YB-1 [Similar Products]
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 NCBI Summary for YBX1    This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]
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 UniProt Comments for YBX1    Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro.
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 Research Articles on YBX1    1. Kindlin-2 is up-regulated in glioma cells and acts as an oncogene. It is an independent risk factor for poor prognosis. The Kindlin-2/YB-1/beta-catenin complex promotes EGFR transcription and contributes to glioma progression. Kindlin-2 is a potential diagnostic and prognostic marker in glioma, and inhibition of Kindlin-2 may be a novel strategy for glioma treatment.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with YBX1 recombinant proteinPathways associated with YBX1 recombinant protein
 Reference Product  PubMed Publications
 TFAP2A recombinant protein  >7 publications with YBX1 and TFAP2A
 tat recombinant protein  >5 publications with YBX1 and tat
 PCNA recombinant protein  >4 publications with YBX1 and PCNA
 PURA recombinant protein  >4 publications with YBX1 and PURA
 SMAD3 recombinant protein  >2 publications with YBX1 and SMAD3
 FUS recombinant protein  >2 publications with YBX1 and FUS
 TP53 recombinant protein  >2 publications with YBX1 and TP53
 CTCF recombinant protein  >2 publications with YBX1 and CTCF
 SLC6A4 recombinant protein  >1 publications with YBX1 and SLC6A4
 NFYB recombinant protein  >1 publications with YBX1 and NFYB
 Products by Pathway  Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 SIDS Susceptibility Pathways antibodies  SIDS Susceptibility Pathways Diagram
 Signaling Events Mediated By PTP1B Pathway antibodies  Signaling Events Mediated By PTP1B Pathway Diagram
 MRNA Splicing Pathway antibodies  MRNA Splicing Pathway Diagram
 MRNA Splicing - Major Pathway antibodies  MRNA Splicing - Major Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
Diseases associated with YBX1 recombinant proteinOrgans/Tissues associated with YBX1 recombinant protein
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >43 publications with YBX1 and Breast Neoplasms
 Nervous System Diseases Antibodies  >15 publications with YBX1 and Nervous System Diseases
 Liver Diseases Antibodies  >15 publications with YBX1 and Liver Diseases
 Immune System Diseases Antibodies  >12 publications with YBX1 and Immune System Diseases
 Liver Neoplasms Antibodies  >10 publications with YBX1 and Liver Neoplasms
 Disease Models, Animal Antibodies  >9 publications with YBX1 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >8 publications with YBX1 and Neoplasm Metastasis
 Lung Diseases Antibodies  >8 publications with YBX1 and Lung Diseases
 Kidney Diseases Antibodies  >7 publications with YBX1 and Kidney Diseases
 Carcinoma, Hepatocellular Antibodies  >6 publications with YBX1 and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >83 publications with YBX1 and Liver
 Brain Antibodies  >36 publications with YBX1 and Brain
 Blood Antibodies  >29 publications with YBX1 and Blood
 Lung Antibodies  >26 publications with YBX1 and Lung
 Kidney Antibodies  >26 publications with YBX1 and Kidney
 Vascular Antibodies  >16 publications with YBX1 and Vascular
 Muscle Antibodies  >16 publications with YBX1 and Muscle
 Thyroid Antibodies  >13 publications with YBX1 and Thyroid
 Mammary Gland Antibodies  >11 publications with YBX1 and Mammary Gland
 Embryonic Tissue Antibodies  >11 publications with YBX1 and Embryonic Tissue
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