NP_595189.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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Molecular Weight
46,409 Da
NCBI Official Full Name
homocysteine synthase Met17
NCBI Protein Information
homocysteine synthase Met17
UniProt Protein Name
Homocysteine synthase
UniProt Synonym Protein Names
O-acetylhomoserine sulfhydrylase
UniProt Synonym Gene Names
UniProt Comments for SPBC428.11
Catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway (PubMed:11754480, PubMed:6526818). Can also use O-succinyl-L-homoserine and L-homoserine as substrates (PubMed:6526818). Has also cysteine synthase (O-acetylserine sulfhydrylase) activity in vitro, but in S.pombe, it seems only to be involved in the alternative pathway of methionine biosynthesis under cysteine deficiency conditions (PubMed:11754480).
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Pathways associated with SPBC428.11 recombinant protein
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