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OC recombinant protein :: Osteocalcin (OC) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2009075 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $140 +1 FREE 8GB USB
0.05 mg  /  $265 +1 FREE 8GB USB
0.1 mg  /  $410 +1 FREE 8GB USB
0.2 mg  /  $505 +1 FREE 8GB USB
0.5 mg  /  $980 +1 FREE 8GB USB
1 mg  /  $1,445 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Osteocalcin (OC), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Osteocalcin (OC)

 Product Gene Name   

OC recombinant protein

[Similar Products]
 Matching Pairs    Antibody: Osteocalcin (OC) (MBS2003553)
Antigen: Osteocalcin (OC) (MBS2009075)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with two N-terminal Tags, His-tag and GST-tag, its sequence is listed below.
 Chromosome Location    Chromosome: 3; NC_000069.6 (88383495..88384466, complement). Location: 3 F1; 3 38.82 cM
 3D Structure    ModBase 3D Structure for P86546
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as freeze-dried powder form in Phosphate buffered saline(PBS), pH 7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300.
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 Organism    Mus musculus (Mouse)
 Expression System    Prokaryotic expression
 Residues    Ala14~Ile95 (Accession # P86546) with two N-terminal Tags, His-tag and GST-tag
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of OC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for OC recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for OC recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-PAGE of OC recombinant protein    OC recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for OC. It may not necessarily be applicable to this product.
 NCBI GI #    6671634
 NCBI GeneID    12096
 NCBI Accession #    NP_031567.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_007541.3 [Other Products]
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 UniProt Primary Accession #    P86546 [Other Products]
 UniProt Secondary Accession #    P04641 [Other Products]
 UniProt Related Accession #    P86546 [Other Products]
 Molecular Weight    41.0kDa
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 NCBI Official Full Name    osteocalcin isoform 1
 NCBI Official Synonym Full Names    bone gamma carboxyglutamate protein
 NCBI Official Symbol    Bglap [Similar Products]
 NCBI Official Synonym Symbols   
OC; OG1; mOC-A; Bglap1
[Similar Products]
 NCBI Protein Information    osteocalcin; BGP; bone Gla protein; bone gamma carboxyglutamate protein 1; gamma-carboxyglutamic acid-containing protein
 UniProt Protein Name    Osteocalcin
 UniProt Synonym Protein Names   
Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein
 UniProt Gene Name    Bglap [Similar Products]
 UniProt Synonym Gene Names    BGP [Similar Products]
 UniProt Entry Name    OSTCN_MOUSE
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 UniProt Comments for OC    Function: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.

Subcellular location: Secreted.

Tissue specificity: Bone.

Post-translational modification: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.

Sequence similarities: Belongs to the osteocalcin/matrix Gla protein family.Contains 1 Gla (gamma-carboxy-glutamate) domain.
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 Research Articles on OC    1. This study reveals that the skeleton via osteocalcin influences cognition and contributes to the maternal influence on fetal brain development.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with OC recombinant proteinOrgans/Tissues associated with OC recombinant protein
 Disease Name  Pubmed Publications
 Bone Diseases Antibodies  >9 publications with OC and Bone Diseases
 Osteoporosis Antibodies  >5 publications with OC and Osteoporosis
 Neoplasms Antibodies  >4 publications with OC and Neoplasms
 Inflammation Antibodies  >2 publications with OC and Inflammation
 Weight Loss Antibodies  >1 publications with OC and Weight Loss
 Pain Antibodies  >1 publications with OC and Pain
 Hypertension Antibodies  >1 publications with OC and Hypertension
 Cardiovascular Diseases Antibodies  >1 publications with OC and Cardiovascular Diseases
 Brain Injuries Antibodies  >1 publications with OC and Brain Injuries
 Hemorrhage Antibodies  >1 publications with OC and Hemorrhage
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >2 publications with OC and Embryonic Tissue
 Joint Antibodies  >1 publications with OC and Joint
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