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tolC recombinant protein :: Outer membrane protein tolC (tolC) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1054270 tolC recombinant protein
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Outer membrane protein tolC (tolC), Recombinant Protein

 Also Known As   

Recombinant Escherichia coli Outer membrane protein tolC (tolC)

 Product Synonym Names    Recombinant Outer membrane protein tolC (tolC); Outer membrane protein tolC
 Product Gene Name   

tolC recombinant protein

[Similar Products]
 Product Synonym Gene Name    tolC; mtcB, mukA, refI [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    23-493
 Sequence    ENLMQVYQQA RLSNPELRKS AADRDAAFEK INEARSPLLP QLGLGADYTY SNGYRDANGI NSNATSASLQ LTQSIFDMSK WRALTLQEKA AGIQDVTYQT DQQTLILNTA TAYFNVLNAI DVLSYTQAQK EAIYRQLDQT TQRFNVGLVA ITDVQNARAQ YDTVLANEVT ARNNLDNAVE QLRQITGNYY PELAALNVEN FKTDKPQPVN ALLKEAEKRN LSLLQARLSQ DLAREQIRQA QDGHLPTLDL TASTGISDTS YSGSKTRGAA GTQYDDSNMG QNKVGLSFSL PIYQGGMVNS QVKQAQYNFV GASEQLESAH RSVVQTVRSS FNNINASISS INAYKQAVVS AQSSLDAMEA GYSVGTRTIV DVLDATTTLY NAKQELANAR YNYLINQLNI KSALGTLNEQ DLLALNNALS KPVSTNPENV APQTPEQNAI ADGYAPDSPA PVVQQTSART TTSNGHNPFR N
 Chromosome Location    NC_000913.2 (3176137..3177618)
 3D Structure    ModBase 3D Structure for P02930
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Escherichia coli (strain K12)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of tolC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for tolC. It may not necessarily be applicable to this product.
 NCBI GI #    90111528
 NCBI GeneID    947521
 NCBI Accession #    NP_417507.2 [Other Products]
 NCBI GenBank Nucleotide #    NC_000913.2 [Other Products]
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 UniProt Primary Accession #    P02930 [Other Products]
 UniProt Secondary Accession #    Q2M9G5 [Other Products]
 Molecular Weight    53,741 Da [Similar Products]
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 NCBI Official Full Name    transport channel
 NCBI Official Symbol    tolC [Similar Products]
 NCBI Official Synonym Symbols   
colE1-i; ECK3026; JW5503; mtcB; mukA; refI; toc; weeA
[Similar Products]
 NCBI Protein Information    transport channel
 UniProt Protein Name    Outer membrane protein TolC
 Protein Family    Outer membrane protein
 UniProt Gene Name    tolC [Similar Products]
 UniProt Synonym Gene Names    mtcB; mukA; refI [Similar Products]
 UniProt Entry Name    TOLC_ECOLI
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 NCBI Summary for tolC    TolC, MdtQ, MdtP and CusC are paralogs. [More information is available at EcoGene: EG11009]. TolC is an outer membrane porin involved in the efflux of several hydrophobic and amphipathic molecules. [More information is available at EcoCyc: EG11009].
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 UniProt Comments for tolC    Function: Required for proper expression of outer membrane protein genes such as ompF, nmpC, protein 2, hemolysin, colicin V, or colicin E1. May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria.

Subunit structure: Homotrimer that assembles to form a continuous, solvent-accessible conduit: a 'channel-tunnel' over 140 Angstroms long that spans both the outer membrane and periplasmic space. The periplasmic or proximal end of the tunnel is sealed by sets of coiled helices. Ref.8

Subcellular location: Cell outer membrane; Multi-pass membrane protein Ref.8.

Sequence similarities: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. [View classification]

Sequence caution: The sequence AAA69203.1 differs from that shown. Reason: Erroneous initiation. The sequence CAA24751.1 differs from that shown. Reason: Erroneous initiation. The sequence CAA24914.1 differs from that shown. Reason: The sequence CAA37982.1 differs from that shown. Reason: Erroneous initiation.
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 Research Articles on tolC    1. The TolC enhancement of extreme-acid survival includes Gad induction, but TolC-dependent growth rates below pH 6.5 do not involve Gad.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with tolC recombinant proteinPathways associated with tolC recombinant protein
 Reference Product  PubMed Publications
 acrB recombinant protein  >160 publications with tolC and acrB
 acrA recombinant protein  >124 publications with tolC and acrA
 macA recombinant protein  >16 publications with tolC and macA
 acrF recombinant protein  >14 publications with tolC and acrF
 macB recombinant protein  >14 publications with tolC and macB
 acrD recombinant protein  >13 publications with tolC and acrD
 emrA recombinant protein  >9 publications with tolC and emrA
 emrB recombinant protein  >7 publications with tolC and emrB
 mdtF recombinant protein  >2 publications with tolC and mdtF
 Products by Pathway  Pathway Diagram
 Bacterial Secretion System Pathway antibodies  Bacterial Secretion System Pathway Diagram
 Bacterial Secretion System Pathway antibodies  Bacterial Secretion System Pathway Diagram
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