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OXTR recombinant protein :: Oxytocin Receptor (OXTR) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2009192 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $135 +1 FREE 8GB USB
0.05 mg  /  $245 +1 FREE 8GB USB
0.1 mg  /  $365 +1 FREE 8GB USB
0.2 mg  /  $450 +1 FREE 8GB USB
0.5 mg  /  $870 +1 FREE 8GB USB
1 mg  /  $1,280 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Oxytocin Receptor (OXTR), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Oxytocin Receptor (OXTR)

 Product Gene Name   

OXTR recombinant protein

[Similar Products]
 Matching Pairs    Antibody: Oxytocin Receptor (OXTR) (MBS2002159)
Antigen: Oxytocin Receptor (OXTR) (MBS2009192)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with two N-terminal Tags, His-tag and GST-tag, its sequence is listed below.
MRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF - RTVKMTFII VLAFIVCWTP FFFVQMWSVW DANAPKEASA FIIVMLLASL NSCCNPWIYM LFTGHLFHEL VQRFLCCSAS YLKGRRLGET SASKKSNSSS FVLSHRS
 Chromosome Location    Chromosome: 3; NC_000003.11 (8792094..8811300, complement). Location: 3p25
 OMIM    167055
 3D Structure    ModBase 3D Structure for P30559
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 Host    E Coli
 Species Reactivity    Homo sapiens
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 Purity/Purification    > 95%
 Form/Format    20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
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 Tissue Specificity    Ovary.
 Subcellular Location    Cell membrane; Multi-pass membrane protein.
 Residues    Arg272~Ser377 with two N-terminal Tags, His-tag and GST-tag
 Traits    Freeze-dried powder
 Predicted isoelectric point    5.5
 Predicted Molecular Mass    42.1kDa
 Accurate Molecular Mass    42kDa as determined by SDS-PAGE reducing conditions.
 Reconstitution    Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of OXTR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for OXTR recombinant protein   

SDS-PAGE; WB; ELISA; IP; CoIP; ReporterAssays; Purification; Amine Reactive Labeling.(May be suitable for use in other assays to be determined by the end user.)

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 Sequence of OXTR recombinant protein    OXTR recombinant protein Sequence image
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 SDS-PAGE of OXTR recombinant protein    OXTR recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for OXTR. It may not necessarily be applicable to this product.
 NCBI GI #    32307152
 NCBI GeneID    5021
 NCBI Accession #    NP_000907.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000916.3 [Other Products]
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 UniProt Primary Accession #    P30559 [Other Products]
 UniProt Secondary Accession #    Q15071 [Other Products]
 UniProt Related Accession #    P30559 [Other Products]
 Molecular Weight    39.2kDa
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 NCBI Official Full Name    oxytocin receptor
 NCBI Official Synonym Full Names    oxytocin receptor
 NCBI Official Symbol    OXTR [Similar Products]
 NCBI Official Synonym Symbols   
OT-R
[Similar Products]
 NCBI Protein Information    oxytocin receptor
 UniProt Protein Name    Oxytocin receptor
 Protein Family    Oxytocin receptor
 UniProt Gene Name    OXTR [Similar Products]
 UniProt Synonym Gene Names    OT-R [Similar Products]
 UniProt Entry Name    OXYR_HUMAN
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 NCBI Summary for OXTR    The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]
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 UniProt Comments for OXTR    OXTR: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p25

Cellular Component: cell-cell adherens junction; microvillus; integral to plasma membrane; apical plasma membrane; plasma membrane

Molecular Function: oxytocin receptor activity; peptide hormone binding; peptide binding; vasopressin receptor activity

Biological Process: lactation; response to peptide hormone stimulus; response to anoxia; heart development; female pregnancy; positive regulation of synaptic transmission, glutamatergic; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; muscle contraction; response to drug; maternal behavior; eating behavior; response to amphetamine; positive regulation of synaptic transmission, GABAergic; social behavior; response to cocaine; sleep; memory; cellular response to hormone stimulus; G-protein coupled receptor protein signaling pathway; positive regulation of synaptogenesis; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; suckling behavior; gut development; response to cytokine stimulus; maternal process involved in parturition; positive regulation of vasoconstriction; sperm ejaculation; response to progesterone stimulus; positive regulation of blood pressure
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 Research Articles on OXTR    1. OXTR SNP rs237885 did not associate with maternal behavior, but it did associate with pre-natal (but not post-natal) depression score.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with OXTR recombinant proteinPathways associated with OXTR recombinant protein
 Reference Product  PubMed Publications
 OXT recombinant protein  >49 publications with OXTR and OXT
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with OXTR recombinant proteinOrgans/Tissues associated with OXTR recombinant protein
 Disease Name  Pubmed Publications
 Child Development Disorders, Pervasive Antibodies  >30 publications with OXTR and Child Development Disorders, Pervasive
 Autistic Disorder Antibodies  >30 publications with OXTR and Autistic Disorder
 Cognition Disorders Antibodies  >15 publications with OXTR and Cognition Disorders
 Schizophrenia Antibodies  >7 publications with OXTR and Schizophrenia
 Inflammation Antibodies  >6 publications with OXTR and Inflammation
 Neoplasms Antibodies  >6 publications with OXTR and Neoplasms
 Depressive Disorder Antibodies  >5 publications with OXTR and Depressive Disorder
 Necrosis Antibodies  >3 publications with OXTR and Necrosis
 Pain Antibodies  >2 publications with OXTR and Pain
 Brain Diseases Antibodies  >2 publications with OXTR and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >82 publications with OXTR and Brain
 Uterus Antibodies  >25 publications with OXTR and Uterus
 Embryonic Tissue Antibodies  >5 publications with OXTR and Embryonic Tissue
 Heart Antibodies  >5 publications with OXTR and Heart
 Ovary Antibodies  >4 publications with OXTR and Ovary
 Connective Tissue Antibodies  >3 publications with OXTR and Connective Tissue
 Liver Antibodies  >2 publications with OXTR and Liver
 Lung Antibodies  >2 publications with OXTR and Lung
 Kidney Antibodies  >2 publications with OXTR and Kidney
 Trachea Antibodies  >1 publications with OXTR and Trachea
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