NP_036932.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
P2Y purinoceptor 1
NCBI Official Synonym Full Names
purinergic receptor P2Y, G-protein coupled, 1
NCBI Official Synonym Symbols
NCBI Protein Information
P2Y purinoceptor 1; ATP receptor; P2Y ATP receptor 1; P2 purinoreceptor subclass 2Y
UniProt Protein Name
P2Y purinoceptor 1
UniProt Synonym Protein Names
ATP receptor; Purinergic receptor
UniProt Synonym Gene Names
UniProt Entry Name
P2RY1_RAT
NCBI Summary for P2ry1
G protein-coupled receptor for extracellular ATP; plays a role in ischemic preconditioning (IPC) in heart [RGD, Feb 2006]
UniProt Comments for P2ry1
P2RY1: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1
Cellular Component: postsynaptic membrane; cell surface; mitochondrion; basolateral plasma membrane; apical plasma membrane; dendrite; integral to membrane; plasma membrane
Molecular Function: ATP-activated nucleotide receptor activity; purinergic nucleotide receptor activity, G-protein coupled; protein heterodimerization activity; A1 adenosine receptor binding; ADP binding; ATP binding; ADP-activated nucleotide receptor activity
Biological Process: platelet activation; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); wound healing; regulation of vasodilation; eating behavior; positive regulation of hormone secretion; positive regulation of inositol trisphosphate biosynthetic process; sensory perception of pain; negative regulation of binding; glial cell migration; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; response to mechanical stimulus; positive regulation of transcription from RNA polymerase II promoter; positive regulation of ion transport; positive regulation of protein amino acid phosphorylation; G-protein signaling, adenylate cyclase inhibiting pathway; regulation of receptor activity; adenosine receptor signaling pathway; aging
Research Articles on P2ry1
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Pathways associated with P2ry1 recombinant protein
Diseases associated with P2ry1 recombinant protein
Organs/Tissues associated with P2ry1 recombinant protein
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