NP_073625.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,439 Da
NCBI Official Full Name
P2Y purinoceptor 12
NCBI Official Synonym Full Names
purinergic receptor P2Y12
NCBI Official Synonym Symbols
HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc) [Similar Products]
NCBI Protein Information
P2Y purinoceptor 12
UniProt Protein Name
P2Y purinoceptor 12
UniProt Synonym Protein Names
ADP-glucose receptor; ADPG-R; P2T(AC); P2Y(AC); P2Y(cyc); P2Y12 platelet ADP receptor; P2Y(ADP); SP1999
UniProt Synonym Gene Names
NCBI Summary for P2RY12
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
UniProt Comments for P2RY12
Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.
Research Articles on P2RY12
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Products associated with P2RY12 recombinant protein
Pathways associated with P2RY12 recombinant protein
Diseases associated with P2RY12 recombinant protein
Organs/Tissues associated with P2RY12 recombinant protein
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