Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow PFDN4  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • CDCA2 Antibody
 • Insertion element IS1 protein insA (insA) Recombinant Protein
 • glycerol kinase 5 (putative) (GK5) ELISA Kit
 • CUL2 Antibody
 • 2',5'-Oligoadenylate Synthetase 1 (OAS1) ELISA Kit
 • ADH1C Antibody
 • GPR52 Antibody
 • Beta-galactosidase (GLB1) Recombinant Protein
 • CD226 antigen (CD226) ELISA Kit
 • 3-isopropylmalate dehydratase large subunit (leuC) Recombinant Protein
 • Glucosidase Alpha, Acid (GaA) Antibody
 • Tissue, Total Protein Adult Normal, Brain Lysate
 • p53 Antibody
 • Reelin (RELN) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

PFDN4 recombinant protein

Scan QR to view Datasheet Catalog #    MBS204012
SDS-PAGE
Unit / Price
0.05 mg  /  $375 +1 FREE 8GB USB
0.25 mg  /  $925 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PFDN4, Recombinant Protein

 Also Known As   

PFDN4, 1-134aa, Human, His tag, E Coli

 Product Synonym Names    Prefoldin subunit 4; Protein C-1; PFD4; Protein C1; Prefoldin 4; Prefoldin4
 Product Gene Name   

PFDN4 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    MGSSHHHHHH SSGLVPRGSH MAATMKKAAA EDVNVTFEDQ QKINKFARNT SRITELKEEI EVKKKQLQNL EDACDDIMLA DDDCLMIPYQ IGDVFISHSQ EETQEMLEEA KKNLQEEIDA LESRVESIQR VLADLKVQLY AKFGSNINLE ADES
Section Bar
Section Bar
 Purity/Purification    > 90% by SDS - PAGE
 Form/Format    Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 10% glycerol, 50mM NaCl
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
Section Bar
 Antigen Species    Human
 Tag    His-tag
 Expression System    E Coli
Section Bar
 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of PFDN4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for PFDN4 recombinant protein

   Prefoldin subunit 4, also known PFDN4, is a member of the prefoldin beta subunit family. PFDN4 is a heterohexameric chaperone protein which has the ability to capture unfolded actin and is a possible transcription factor. Six prefoldin polypeptides, prefoldin 1-6, have been identified. Recombinant human PFDN4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
 Product Categories/Family for PFDN4 recombinant protein    Heat Shock Proteins
 Applications Tested/Suitable for PFDN4 recombinant protein   

SDS-PAGE

Section Bar
 SDS-PAGE of PFDN4 recombinant protein    PFDN4 recombinant protein SDS-PAGE image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PFDN4. It may not necessarily be applicable to this product.
 NCBI GI #    12408677
 NCBI GeneID    5203
 NCBI Accession #    NP_002614 [Other Products]
 NCBI GenBank Nucleotide #    NM_002623.3 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q5TD11; Q92779 [Other Products]
 UniProt Related Accession #    Q9NQP4 [Other Products]
 Molecular Weight    17.4 kDa (154aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Table BarTOPTable Bar
 NCBI Official Full Name    prefoldin subunit 4
 NCBI Official Synonym Full Names    prefoldin subunit 4
 NCBI Official Symbol    PFDN4 [Similar Products]
 NCBI Official Synonym Symbols   
C1; PFD4
[Similar Products]
 NCBI Protein Information    prefoldin subunit 4; prefoldin 4; protein C-1
 UniProt Protein Name    Prefoldin subunit 4
 UniProt Synonym Protein Names   
Protein C-1
 Protein Family    Prefoldin
 UniProt Gene Name    PFDN4 [Similar Products]
 UniProt Synonym Gene Names    PFD4 [Similar Products]
 UniProt Entry Name    PFD4_HUMAN
Section Bar
 NCBI Summary for PFDN4    This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for PFDN4    PFDN4: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Belongs to the prefoldin subunit beta family.

Chromosomal Location of Human Ortholog: 20q13.2

Cellular Component: mitochondrion; cytoplasm; nucleus; prefoldin complex; cytosol

Molecular Function: protein binding; chaperone binding; unfolded protein binding

Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding
Table BarTOPTable Bar
 

Product References and Citations for PFDN4 recombinant protein

   Vainberq IE., et al. (1998) Cell. 29(5):863-73.
Brinke A., et al. (1997) Genomics. 45:105-112.
Section Bar
 Research Articles on PFDN4    1. PFDN4 inhibition resulted in an increase in cell growth and invasiveness in colorectal cancer cell lines.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with PFDN4 recombinant proteinPathways associated with PFDN4 recombinant protein
 Reference Product  PubMed Publications
 CCT2 recombinant protein  >1 publications with PFDN4 and CCT2
 Products by Pathway  Pathway Diagram
 Chaperonin-mediated Protein Folding Pathway antibodies  Chaperonin-mediated Protein Folding Pathway Diagram
 Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway antibodies  Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Prefoldin Mediated Transfer Of Substrate To CCT/TriC Pathway antibodies  Prefoldin Mediated Transfer Of Substrate To CCT/TriC Pathway Diagram
 Protein Folding Pathway antibodies  Protein Folding Pathway Diagram
Diseases associated with PFDN4 recombinant proteinOrgans/Tissues associated with PFDN4 recombinant protein
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >2 publications with PFDN4 and Immune System Diseases
 Inflammation Antibodies  >1 publications with PFDN4 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >2 publications with PFDN4 and Skin
 Stomach Antibodies  >2 publications with PFDN4 and Stomach
 Embryonic Tissue Antibodies  >1 publications with PFDN4 and Embryonic Tissue
 Pancreas Antibodies  >1 publications with PFDN4 and Pancreas
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions