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Pou4f1 recombinant protein :: POU domain, class 4, transcription factor 1 (Pou4f1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS959303 Pou4f1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $525 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $695 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $770 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $840 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $930 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,045 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,060 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,080 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,080 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,535 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,585 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,650 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,060 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

POU domain, class 4, transcription factor 1 (Pou4f1), Recombinant Protein

 Also Known As   

Recombinant Rat POU domain, class 4, transcription factor 1 (Pou4f1)

 Product Gene Name   

Pou4f1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-128aa, Full length protein
 Sequence    RRIKLGVTQA DVGSALANLK IPGVGSLSQS TICRFESLTL SHNNMIALKP ILQAWLEEAE GAQREKMNKP ELFNGGEKKR KRTSIAAPEK RSLEAYFAVQ PRPSSEKIAA IAEKLDLKKN VVRVWFCN
 3D Structure    ModBase 3D Structure for P20266
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Pou4f1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Pou4f1. It may not necessarily be applicable to this product.
 NCBI GI #    672078989
 NCBI GeneID    114503
 NCBI Accession #    XP_008769153.1 [Other Products]
 NCBI GenBank Nucleotide #    XM_008770931.2 [Other Products]
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 UniProt Primary Accession #    P20266 [Other Products]
 UniProt Secondary Accession #    Q91XM4 [Other Products]
 UniProt Related Accession #    P20266 [Other Products]
 Molecular Weight    34,068 Da
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 NCBI Official Full Name    LOW QUALITY PROTEIN: POU domain, class 4, transcription factor 1 isoform X1
 NCBI Official Synonym Full Names    POU class 4 homeobox 1
 NCBI Official Symbol    Pou4f1 [Similar Products]
 NCBI Official Synonym Symbols   
Brn3a; brn-3A
[Similar Products]
 NCBI Protein Information    POU domain, class 4, transcription factor 1; LOW QUALITY PROTEIN: POU domain, class 4, transcription factor 1
 UniProt Protein Name    POU domain, class 4, transcription factor 1
 UniProt Synonym Protein Names   
Brain-specific homeobox/POU domain protein 3A; Brain-3A; Brn-3A
 Protein Family    POU domain, class 4, transcription factor
 UniProt Gene Name    Pou4f1 [Similar Products]
 UniProt Synonym Gene Names    Brn-3; Brn3; Brn3a; Brain-3A; Brn-3A [Similar Products]
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 NCBI Summary for Pou4f1    transcription factor containing the Pit1-Oct1-Unc86 (POU) domain; regulates expression of Trk receptors and Bcl-2 family members; associated with sensory neuron survival [RGD, Feb 2006]
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 UniProt Comments for Pou4f1    Multifunctional transcription factor with different regions mediating its different effects (PubMed:10640682). Acts by binding (via its C-terminal domain) to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes. Regulates the expression of specific genes involved in differentiation and survival within a subset of neuronal lineages (PubMed:11053412). It has been shown that activation of some of these genes requires its N-terminal domain, maybe through a neuronal-specific cofactor. Ativates BCL2 expression and protects neuronal cells from apoptosis (via the N-terminal domain). Induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins. Exerts its major developmental effects in somatosensory neurons and in brainstem nuclei involved in motor control. Stimulates the binding affinity of the nuclear estrogene receptor ESR1 to DNA estrogen response element (ERE), and hence modulates ESR1-induced transcriptional activity. May positively regulate POU4F2 and POU4F3. Regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord. Plays a role in TNFSF11-mediated terminal osteoclast differentiation. Negatively regulates its own expression interacting directly with a highly conserved autoregulatory domain surrounding the transcription initiation site ().
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 Research Articles on Pou4f1    1. phenotypic and molecular changes that may represent an effort to resist degeneration and/or preferential survival of m+RGCs capable of synthesizing Brn3a.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Pou4f1 recombinant proteinOrgans/Tissues associated with Pou4f1 recombinant protein
 Reference Product  PubMed Publications
 Pax3 recombinant protein  >2 publications with Pou4f1 and Pax3
 Organ/Tissue Name  Pubmed Publications
 Dorsal Root Ganglion Antibodies  >58 publications with Pou4f1 and Dorsal Root Ganglion
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