NP_001096137
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32.0 kDa (285aa), confirmed by MALDI-TOF
NCBI Official Full Name
proteasome subunit alpha type-4 isoform 1
NCBI Official Synonym Full Names
proteasome subunit alpha 4
NCBI Protein Information
proteasome subunit alpha type-4
UniProt Protein Name
Proteasome subunit alpha type-4
UniProt Synonym Protein Names
Macropain subunit C9; Multicatalytic endopeptidase complex subunit C9; Proteasome component C9; Proteasome subunit L
UniProt Synonym Gene Names
NCBI Summary for PSMA4
This gene encodes a core alpha subunit of the 20S proteosome, which is a highly ordered ring-shaped structure composed of four rings of 28 non-identical subunits. Proteasomes cleave peptides in an ATP- and ubiquitin-dependent manner. [provided by RefSeq, Aug 2016]
UniProt Comments for PSMA4
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Product References and Citations for PSMA4 recombinant protein
Kristensen P. et al. (1995) Biochem. Biophys. Res.Commun. 205: 1785-1789.; Morimoto Y. et al. (1995) J. Biochem. 117: 471-474
Research Articles on PSMA4
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with PSMA4 recombinant protein
Pathways associated with PSMA4 recombinant protein
Diseases associated with PSMA4 recombinant protein
Organs/Tissues associated with PSMA4 recombinant protein
|