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PRDX2 recombinant protein :: Peroxiredoxin 2 (PRDX2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2010800 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
SDS-PAGE
Unit / Price
0.01 mg  /  $140 +1 FREE 8GB USB
0.05 mg  /  $270 +1 FREE 8GB USB
0.1 mg  /  $420 +1 FREE 8GB USB
0.2 mg  /  $515 +1 FREE 8GB USB
0.5 mg  /  $990 +1 FREE 8GB USB
1 mg  /  $1,475 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Peroxiredoxin 2 (PRDX2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Peroxiredoxin 2 (PRDX2)

 Product Gene Name   

PRDX2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2010800 Technical Datasheet    Technical Datasheet PDF
 Sequence    AQIGK SAPDFTATAV VDGAFKEIKL SDYRGKYVVL FFYPLDFTFV CPTEIIAFSD HAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTKS LSQNYGVLKN DEGIAYRGLF IIDAKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQY
 Chromosome Location    Chromosome: 8; NC_000074.6 (84969648..84974317). Location: 8 C3; 8 41.4 cM
 3D Structure    ModBase 3D Structure for Q61171
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 Host    E.coli
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 Purity/Purification    > 90%
 Form/Format    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
 Concentration    Original Concentration: 200ug/mL (lot specific)
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 Organism Species    Mus musculus (Mouse)
 Residues    Ala6~Tyr164
 Tags    N-terminal His Tag
 Subcellular Location    Cytoplasm
 Traits    Freeze-dried powder
 Predicted isoelectric point    6.0
 Predicted Molecular Mass    18.8kDa
 Accurate Molecular Mass    18kDa as determined by SDS-PAGE reducing conditions.
 Usage    Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of PRDX2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for PRDX2 recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for PRDX2 recombinant protein   

Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)

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 SDS-PAGE of PRDX2 recombinant protein    PRDX2 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for PRDX2. It may not necessarily be applicable to this product.
 NCBI GI #    148747558
 NCBI GeneID    21672
 NCBI Accession #    NP_035693.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_011563.5 [Other Products]
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 UniProt Primary Accession #    Q61171 [Other Products]
 UniProt Secondary Accession #    O88376; Q60796; Q9CWJ4; Q9DB49 [Other Products]
 UniProt Related Accession #    Q61171 [Other Products]
 Molecular Weight    19.1kDa
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 NCBI Official Full Name    peroxiredoxin-2
 NCBI Official Synonym Full Names    peroxiredoxin 2
 NCBI Official Symbol    Prdx2 [Similar Products]
 NCBI Official Synonym Symbols   
TR; PRP; TPx; TSA; TDX1; NkefB; PrxII; TPx-B; Tdpx1; Torin; Band-8; AL022839
[Similar Products]
 NCBI Protein Information    peroxiredoxin-2; Prx II-1; Calpromotin; protector protein; thioredoxin reductase; thioredoxin peroxidase 1; Trx dependent peroxide reductase 1; thiol specific antioxidant protein; thiol-specific antioxidant protein; thioredoxin dependent peroxide reductase 1; thioredoxin-dependent peroxide reductase 1
 UniProt Protein Name    Peroxiredoxin-2
 UniProt Synonym Protein Names   
Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1
 Protein Family    Peroxiredoxin
 UniProt Gene Name    Prdx2 [Similar Products]
 UniProt Synonym Gene Names    Tdpx1; Tpx; TSA [Similar Products]
 UniProt Entry Name    PRDX2_MOUSE
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 UniProt Comments for PRDX2    PRDX2: a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). May have a proliferative effect and play a role in cancer development or progression. Three splice-variant isoforms have been identified.

Protein type: EC 1.11.1.15; Oxidoreductase

Cellular Component: mitochondrion; cytoplasm; cytosol; myelin sheath

Molecular Function: antioxidant activity; protein binding; selenium binding; peroxidase activity; thioredoxin peroxidase activity; peroxiredoxin activity; oxidoreductase activity

Biological Process: negative regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of blood coagulation; removal of superoxide radicals; thymus development; activation of MAPK activity; respiratory burst during acute inflammatory response; homeostasis of number of cells; response to lipopolysaccharide; negative regulation of T cell differentiation; regulation of apoptosis; T cell proliferation; hydrogen peroxide catabolic process; inhibition of NF-kappaB transcription factor; hydrogen peroxide metabolic process; negative regulation of neuron apoptosis; response to oxidative stress; regulation of hydrogen peroxide metabolic process
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 Research Articles on PRDX2    1. results suggest that inactivation of PrxII is important for the stability of FoxO1 protein, which subsequently mediates Foxp3( ) Treg cell development, thereby attenuating colonic inflammation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PRDX2 recombinant proteinDiseases associated with PRDX2 recombinant protein
 Products by Pathway  Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >31 publications with PRDX2 and Neoplasms
 Carcinoma Antibodies  >14 publications with PRDX2 and Carcinoma
 Nervous System Diseases Antibodies  >8 publications with PRDX2 and Nervous System Diseases
 Inflammation Antibodies  >7 publications with PRDX2 and Inflammation
 Lung Diseases Antibodies  >5 publications with PRDX2 and Lung Diseases
 Cardiovascular Diseases Antibodies  >5 publications with PRDX2 and Cardiovascular Diseases
 Liver Diseases Antibodies  >5 publications with PRDX2 and Liver Diseases
 Leukemia, Myeloid Antibodies  >4 publications with PRDX2 and Leukemia, Myeloid
 Brain Diseases Antibodies  >4 publications with PRDX2 and Brain Diseases
 Liver Neoplasms Antibodies  >4 publications with PRDX2 and Liver Neoplasms
Organs/Tissues associated with PRDX2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >12 publications with PRDX2 and Brain
 Ovary Antibodies  >5 publications with PRDX2 and Ovary
 Testis Antibodies  >2 publications with PRDX2 and Testis
 Embryonic Tissue Antibodies  >2 publications with PRDX2 and Embryonic Tissue
 Lymph Node Antibodies  >1 publications with PRDX2 and Lymph Node
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