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PRDX5 recombinant protein :: Peroxiredoxin 5 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS203340
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Peroxiredoxin 5 (PRDX5), Recombinant Protein

 Also Known As   

Peroxiredoxin 5, 53-214aa, Human, E Coli (Bioactivity Validated)

 Product Synonym Names    Peroxiredoxin 5; ACR1; AOEB116; B116; PLP; PMP20; PRDX5; PRXV; SBBI10; AOEB166; PRDX 5; Thioredoxin reductase.
 Product Gene Name   

PRDX5 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MAPIKVGDAI PAVEVFEGEP GNKVNLAELF KGKKGVLFGV PGAFTPGCSK THLPGFVEQA EALKAKGVQV VACLSVNDAF VTGEWGRAHK AEGKVRLLAD PTGAFGKETD LLLDDSLVSI FGNRRLKRFS MVVQDGIVKA LNVEPDGTGL TCSLAPNIIS QL
 OMIM    AF231705 mRNA
 3D Structure    ModBase 3D Structure for P30044
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 Host    E Coli
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 Purity/Purification    > 95% by SDS-PAGE
 Form/Format    Liquid. In 20 mM HEPES buffer (pH 7.4).
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Endotoxin Level    < 1.0 EU per 1 microgram of protein (determined by LAL method)
 Biological Activity    Specific activity is >2,000 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for 1minute.
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of PRDX5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for PRDX5 recombinant protein

   Peroxiredoxin 5, also known as PRDX5, is a member of the peroxiredoxin family of antioxidant enzymes, which reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. This protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. It has been reported that peroxiredoxin 5 is involved in intracellular redox signaling. Recombinant Peroxiredoxin 5 protein was expressed in E Coli and purified by using conventional chromatography techniques.
 Product Categories/Family for PRDX5 recombinant protein    Redox Proteins
 Applications Tested/Suitable for PRDX5 recombinant protein   

SDS-PAGE

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 SDS-Page of PRDX5 recombinant protein    PRDX5 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for PRDX5. It may not necessarily be applicable to this product.
 NCBI GI #    6912238
 NCBI GeneID    25824
 NCBI Accession #    NP_036226 [Other Products]
 NCBI GenBank Nucleotide #    NM_012094.4 [Other Products]
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 UniProt Primary Accession #    P30044 [Other Products]
 UniProt Secondary Accession #    Q14CK0; Q6IAF2; Q9UBU5; Q9UJU4; Q9UKX4; A6NC19; A6NG06; B7ZLJ4; B7ZVW3 [Other Products]
 UniProt Related Accession #    P30044 [Other Products]
 Molecular Weight    17.0 kDa (162aa), confirmed by MALDI-TOF. [Similar Products]
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 NCBI Official Full Name    peroxiredoxin-5, mitochondrial isoform L
 NCBI Official Synonym Full Names    peroxiredoxin 5
 NCBI Official Symbol    PRDX5 [Similar Products]
 NCBI Official Synonym Symbols   
PLP; ACR1; B166; PRXV; PMP20; PRDX6; prx-V; SBBI10; AOEB166; HEL-S-55
[Similar Products]
 NCBI Protein Information    peroxiredoxin-5, mitochondrial
 UniProt Protein Name    Peroxiredoxin-5, mitochondrial
 UniProt Synonym Protein Names   
Alu corepressor 1; Antioxidant enzyme B166; AOEB166; Liver tissue 2D-page spot 71B; PLP; Peroxiredoxin V; Prx-V; Peroxisomal antioxidant enzyme; TPx type VI; Thioredoxin peroxidase PMP20
 Protein Family    Peroxiredoxin
 UniProt Gene Name    PRDX5 [Similar Products]
 UniProt Synonym Gene Names    ACR1; AOEB166; Prx-V [Similar Products]
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 NCBI Summary for PRDX5    This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene. [provided by RefSeq, Nov 2017]
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 UniProt Comments for PRDX5    Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
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Product References and Citations for PRDX5 recombinant protein

   Yamashita H., et al. (1999) J Biol Chem. 274 (42):29897-904. ; Declercg JP., et al. (2001) J Mol Biol. 311 (4):751-9.;
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 Research Articles on PRDX5    1. The PRX5 can be used as a predictive biomarker and serves as a putative therapeutic target for the development of clinical treatments for human CRC.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PRDX5 recombinant proteinPathways associated with PRDX5 recombinant protein
 Reference Product  PubMed Publications
 PRDX1 recombinant protein  >20 publications with PRDX5 and PRDX1
 PRDX3 recombinant protein  >19 publications with PRDX5 and PRDX3
 PRDX2 recombinant protein  >15 publications with PRDX5 and PRDX2
 PRDX6 recombinant protein  >14 publications with PRDX5 and PRDX6
 GPX2 recombinant protein  >3 publications with PRDX5 and GPX2
 GSR recombinant protein  >2 publications with PRDX5 and GSR
 CAT recombinant protein  >2 publications with PRDX5 and CAT
 TXN recombinant protein  >2 publications with PRDX5 and TXN
 PARK7 recombinant protein  >1 publications with PRDX5 and PARK7
 TXN2 recombinant protein  >1 publications with PRDX5 and TXN2
 Products by Pathway  Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Selenium Micronutrient Network Pathway antibodies  Selenium Micronutrient Network Pathway Diagram
 TP53 Regulates Metabolic Genes Pathway antibodies  TP53 Regulates Metabolic Genes Pathway Diagram
 Transcriptional Regulation By TP53 Pathway antibodies  Transcriptional Regulation By TP53 Pathway Diagram
 Thioredoxin Pathway antibodies  Thioredoxin Pathway Diagram
Diseases associated with PRDX5 recombinant proteinOrgans/Tissues associated with PRDX5 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >8 publications with PRDX5 and Nervous System Diseases
 Inflammation Antibodies  >7 publications with PRDX5 and Inflammation
 Disease Models, Animal Antibodies  >5 publications with PRDX5 and Disease Models, Animal
 Liver Diseases Antibodies  >4 publications with PRDX5 and Liver Diseases
 Fatty Liver Antibodies  >4 publications with PRDX5 and Fatty Liver
 Necrosis Antibodies  >3 publications with PRDX5 and Necrosis
 Hypertension Antibodies  >3 publications with PRDX5 and Hypertension
 Fibrosis Antibodies  >3 publications with PRDX5 and Fibrosis
 Alopecia Areata Antibodies  >3 publications with PRDX5 and Alopecia Areata
 Cognition Disorders Antibodies  >2 publications with PRDX5 and Cognition Disorders
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >15 publications with PRDX5 and Blood
 Liver Antibodies  >14 publications with PRDX5 and Liver
 Brain Antibodies  >12 publications with PRDX5 and Brain
 Kidney Antibodies  >8 publications with PRDX5 and Kidney
 Lung Antibodies  >8 publications with PRDX5 and Lung
 Muscle Antibodies  >6 publications with PRDX5 and Muscle
 Eye Antibodies  >6 publications with PRDX5 and Eye
 Thyroid Antibodies  >5 publications with PRDX5 and Thyroid
 Vascular Antibodies  >5 publications with PRDX5 and Vascular
 Embryonic Tissue Antibodies  >4 publications with PRDX5 and Embryonic Tissue
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