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PEX5 recombinant protein :: Peroxisomal targeting signal 1 receptor (PEX5) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS950208 PEX5 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $1,065 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,235 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,435 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,485 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,510 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,570 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,585 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,710 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,235 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,240 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,255 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,585 +3 FREE 8GB USB
1 mg (Baculovirus)  /  $2,940 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Peroxisomal targeting signal 1 receptor (PEX5), Recombinant Protein

 Also Known As   

Recombinant Human Peroxisomal targeting signal 1 receptor (PEX5)

 Product Gene Name   

PEX5 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-639aa, Full length protein
 Sequence    MAMRELVEAE CGGANPLMKL AGHFTQDKAL RQEGLRPGPW PPGAPASEAA SKPLGVASED ELVAEFLQDQ NAPLVSRAPQ TFKMDDLLAE MQQIEQSNFR QAPQRAPGVA DLALSENWAQ EFLAAGDAVD VTQDYNETDW SQEFISEVTD PLSVSPARWA EEYLEQSEEK LWLGEPEGTA TDRWYDEYHP EEDLQHTASD FVAKVDDPKL ANSEFLKFVR QIGEGQVSLE SGAGSGRAQA EQWAAEFIQQ QGTSDAWVDQ FTRPVNTSAL DMEFERAKSA IESDVDFWDK LQAELEEMAK RDAEAHPWLS DYDDLTSATY DKGYQFEEEN PLRDHPQPFE EGLRRLQEGD LPNAVLLFEA AVQQDPKHME AWQYLGTTQA ENEQELLAIS ALRRCLELKP DNQTALMALA VSFTNESLQR QACETLRDWL RYTPAYAHLV TPAEEGAGGA GLGPSKRILG SLLSDSLFLE VKELFLAAVR LDPTSIDPDV QCGLGVLFNL SGEYDKAVDC FTAALSVRPN DYLLWNKLGA TLANGNQSEE AVAAYRRALE LQPGYIRSRY NLGISCINLG AHREAVEHFL EALNMQRKSR GPRGEGGAMS ENIWSTLRLA LSMLGQSDAY GAADARDLST LLTMFGLPQ
 OMIM    202370
 3D Structure    ModBase 3D Structure for P50542
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PEX5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for PEX5 recombinant protein

   The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI/Uniprot data below describe general gene information for PEX5. It may not necessarily be applicable to this product.
 NCBI GI #    21361204
 NCBI GeneID    5830
 NCBI Accession #    NP_000310.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000319.4 [Other Products]
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 UniProt Primary Accession #    P50542 [Other Products]
 UniProt Secondary Accession #    Q15115; Q15266; Q96FN7; A8K891; B4DZ45; B7ZAD5; D3DUT8 [Other Products]
 UniProt Related Accession #    P50542 [Other Products]
 Molecular Weight    72,291 Da
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 NCBI Official Full Name    peroxisomal biogenesis factor 5 isoform b
 NCBI Official Synonym Full Names    peroxisomal biogenesis factor 5
 NCBI Official Symbol    PEX5 [Similar Products]
 NCBI Official Synonym Symbols   
PXR1; PBD2A; PBD2B; PTS1R; RCDP5; PTS1-BP
[Similar Products]
 NCBI Protein Information    peroxisomal biogenesis factor 5
 UniProt Protein Name    Peroxisomal targeting signal 1 receptor
 UniProt Synonym Protein Names   
PTS1-BP; Peroxin-5; Peroxisomal C-terminal targeting signal import receptor; Peroxisome receptor 1
 Protein Family    Peroxisome biogenesis protein
 UniProt Gene Name    PEX5 [Similar Products]
 UniProt Synonym Gene Names    PXR1; PTS1 receptor; PTS1R [Similar Products]
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 NCBI Summary for PEX5    The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
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 UniProt Comments for PEX5    Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
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 Research Articles on PEX5    1. these findings lend credit to the idea that inefficient catalase import, when coupled with the role of PEX5 as a redox-regulated import receptor, constitutes a cellular defense mechanism to combat oxidative insults of extra-peroxisomal origin.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PEX5 recombinant proteinPathways associated with PEX5 recombinant protein
 Reference Product  PubMed Publications
 PEX7 recombinant protein  >42 publications with PEX5 and PEX7
 PEX14 recombinant protein  >37 publications with PEX5 and PEX14
 PEX13 recombinant protein  >20 publications with PEX5 and PEX13
 PEX12 recombinant protein  >19 publications with PEX5 and PEX12
 PEX10 recombinant protein  >17 publications with PEX5 and PEX10
 SSTR5 recombinant protein  >1 publications with PEX5 and SSTR5
 PDZK1 recombinant protein  >1 publications with PEX5 and PDZK1
 Products by Pathway  Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
Diseases associated with PEX5 recombinant proteinOrgans/Tissues associated with PEX5 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >32 publications with PEX5 and Nervous System Diseases
 Brain Diseases Antibodies  >31 publications with PEX5 and Brain Diseases
 Zellweger Syndrome Antibodies  >26 publications with PEX5 and Zellweger Syndrome
 Liver Diseases Antibodies  >21 publications with PEX5 and Liver Diseases
 Kidney Diseases Antibodies  >18 publications with PEX5 and Kidney Diseases
 Fatty Liver Antibodies  >6 publications with PEX5 and Fatty Liver
 Nerve Degeneration Antibodies  >4 publications with PEX5 and Nerve Degeneration
 Inflammation Antibodies  >2 publications with PEX5 and Inflammation
 Necrosis Antibodies  >2 publications with PEX5 and Necrosis
 Hyperplasia Antibodies  >1 publications with PEX5 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >29 publications with PEX5 and Liver
 Brain Antibodies  >20 publications with PEX5 and Brain
 Ovary Antibodies  >14 publications with PEX5 and Ovary
 Nerve Antibodies  >7 publications with PEX5 and Nerve
 Muscle Antibodies  >5 publications with PEX5 and Muscle
 Skin Antibodies  >4 publications with PEX5 and Skin
 Heart Antibodies  >4 publications with PEX5 and Heart
 Embryonic Tissue Antibodies  >3 publications with PEX5 and Embryonic Tissue
 Blood Antibodies  >3 publications with PEX5 and Blood
 Eye Antibodies  >1 publications with PEX5 and Eye
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