NP_496462.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
136,873 Da
NCBI Official Full Name
Phosphatidylinositol 3-kinase age-1
NCBI Protein Information
Phosphatidylinositol 3-kinase age-1; hypothetical protein
UniProt Protein Name
Phosphatidylinositol 3-kinase age-1
UniProt Synonym Protein Names
Aging alteration protein 1
UniProt Synonym Gene Names
UniProt Comments for age-1
Phosphatidylinositol 3-kinase homolog that regulates longevity and diapause (PubMed:8700226). Promotes cell survival during embryonic development by recruiting akt-1/2 to the plasma membrane through the production of PtdIns(3,4,5)P3 (PubMed:25383666). Could function in the development or neuroendocrine signaling of the dauer pathway (PubMed:8700226). Mediates susceptibility to enteropathogenic E.coli infection (PubMed:16091039). May negatively regulate AYI interneuron neurite outgrowth (PubMed:22069193). Plays a role in aversive olfactory learning when an odor is associated with food deprivation (PubMed:27383131). Regulates this process by promoting the nuclear relocalization of egl-4 in AWC olfactory neurons after odor conditioning (PubMed:27383131).
Research Articles on age-1
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Pathways associated with age-1 recombinant protein
Diseases associated with age-1 recombinant protein
Organs/Tissues associated with age-1 recombinant protein
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