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LCP1 recombinant protein :: Plastin-2 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS953535
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Unit / Price
0.01 mg (Yeast)  /  $110 +1 FREE 8GB USB
0.01 mg (Baculovirus)  /  $120 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $190 +1 FREE 8GB USB
0.1 mg (Yeast)  /  $285 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $460 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $750 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $1,050 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,180 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,420 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,475 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,565 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,220 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,225 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Plastin-2 (LCP1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Plastin-2

 Product Synonym Names    L-plastin; LC64P; Lymphocyte cytosolic protein 1; LCP-1
 Product Gene Name   

LCP1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS953535 COA    COA PDF
 Sequence Positions    2-627aa; Full Length
 Sequence    ARGSVSDEEM MELREAFAKV DTDGNGYISF NELNDLFKAA CLPLPGYRVR EITENLMATG DLDQDGRISF DEFIKIFHGL KSTDVAKTFR KAINKKEGIC AIGGTSEQSS VGTQHSYSEE EKYAFVNWIN KALENDPDCR HVIPMNPNTN DLFNAVGDGI VLCKMINLSV PDTIDERTIN KKKLTPFTIQ ENLNLALNSA SAIGCHVVNI GAEDLKEGKP YLVLGLLWQV IKIGLFADIE LSRNEALIAL LREGESLEDL MKLSPEELLL RWANYHLENA GCNKIGNFST DIKDSKAYYH LLEQVAPKGD EEGVPAVVID MSGLREKDDI QRAECMLQQA ERLGCRQFVT ATDVVRGNPK LNLAFIANLF NRYPALHKPE NQDIDWGALE GETREERTFR NWMNSLGVNP RVNHLYSDLS DALVIFQLYE KIKVPVDWNR VNKPPYPKLG GNMKKLENCN YAVELGKNQA KFSLVGIGGQ DLNEGNRTLT LALIWQLMRR YTLNILEEIG GGQKVNDDII VNWVNETLRE AKKSSSISSF KDPKISTSLP VLDLIDAIQP GSINYDLLKT ENLNDDEKLN NAKYAISMAR KIGARVYALP EDLVEVNPKM VMTVFACLMG KGMKRV
 OMIM    153430
 3D Structure    ModBase 3D Structure for P13796
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of LCP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for LCP1 recombinant protein

   Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69.
 Product Categories/Family for LCP1 recombinant protein    Cancer
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 SDS-Page of LCP1 recombinant protein    LCP1 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for LCP1. It may not necessarily be applicable to this product.
 NCBI GI #    167614506
 NCBI GeneID    3936
 NCBI Accession #    NP_002289.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002298.4 [Other Products]
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 UniProt Primary Accession #    P13796 [Other Products]
 UniProt Secondary Accession #    Q5TBN4; B2R613; B4DUA0 [Other Products]
 UniProt Related Accession #    P13796 [Other Products]
 Molecular Weight    86.1kD
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 NCBI Official Full Name    plastin-2
 NCBI Official Synonym Full Names    lymphocyte cytosolic protein 1 (L-plastin)
 NCBI Official Symbol    LCP1 [Similar Products]
 NCBI Official Synonym Symbols   
LPL; CP64; PLS2; LC64P; HEL-S-37; L-PLASTIN
[Similar Products]
 NCBI Protein Information    plastin-2
 UniProt Protein Name    Plastin-2
 UniProt Synonym Protein Names   
L-plastin; LC64P; Lymphocyte cytosolic protein 1; LCP-1
 Protein Family    Plastin
 UniProt Gene Name    LCP1 [Similar Products]
 UniProt Synonym Gene Names    PLS2; LCP-1 [Similar Products]
 UniProt Entry Name    PLSL_HUMAN
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 NCBI Summary for LCP1    Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008]
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 UniProt Comments for LCP1    L-plastin: Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Monomer. Interacts with AIF1. Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T- lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.

Protein type: Motility/polarity/chemotaxis; Actin-binding

Chromosomal Location of Human Ortholog: 13q14.3

Cellular Component: actin cytoskeleton; actin filament; actin filament bundle; cytoplasm; cytosol; extracellular space; filopodium; focal adhesion; phagocytic cup; plasma membrane; podosome; ruffle; stress fiber

Molecular Function: actin binding; actin filament binding; calcium ion binding; GTPase binding; identical protein binding

Biological Process: actin filament bundle formation; cell migration; extracellular matrix disassembly; organ regeneration; regulation of intracellular protein transport; T cell activation during immune response
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Product References and Citations for LCP1 recombinant protein

   65-kilodalton protein phosphorylated by interleukin 2 stimulation bears two putative actin-binding sites and two calcium-binding sites.Zu Y., Shigesada K., Nishida E., Kubota I., Kohno M., Hanaoka M., Namba Y.Biochemistry 29:8319-8324(1990) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.Nat. Genet. 36:40-45(2004) The DNA sequence and analysis of human chromosome 13.Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T., Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.Nature 428:522-528(2004)
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 Research Articles on LCP1    1. An NKX3.1 binding site polymorphism in the l-plastin promoter leads to differential gene expression in human prostate cancer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LCP1 recombinant proteinDiseases associated with LCP1 recombinant protein
 Reference Product  PubMed Publications
 ACTG2 recombinant protein  >1 publications with LCP1 and ACTG2
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >7 publications with LCP1 and Immune System Diseases
 Inflammation Antibodies  >5 publications with LCP1 and Inflammation
 Disease Models, Animal Antibodies  >3 publications with LCP1 and Disease Models, Animal
 Fatty Liver Antibodies  >3 publications with LCP1 and Fatty Liver
 Cell Transformation, Neoplastic Antibodies  >2 publications with LCP1 and Cell Transformation, Neoplastic
 Kidney Diseases Antibodies  >2 publications with LCP1 and Kidney Diseases
 Lung Diseases Antibodies  >2 publications with LCP1 and Lung Diseases
 Necrosis Antibodies  >2 publications with LCP1 and Necrosis
 Precancerous Conditions Antibodies  >1 publications with LCP1 and Precancerous Conditions
 Hypertension Antibodies  >1 publications with LCP1 and Hypertension
Organs/Tissues associated with LCP1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >36 publications with LCP1 and Blood
 Bone Antibodies  >8 publications with LCP1 and Bone
 Liver Antibodies  >6 publications with LCP1 and Liver
 Bone Marrow Antibodies  >5 publications with LCP1 and Bone Marrow
 Lymph Node Antibodies  >5 publications with LCP1 and Lymph Node
 Lung Antibodies  >4 publications with LCP1 and Lung
 Eye Antibodies  >4 publications with LCP1 and Eye
 Lymph Antibodies  >4 publications with LCP1 and Lymph
 Kidney Antibodies  >3 publications with LCP1 and Kidney
 Spleen Antibodies  >3 publications with LCP1 and Spleen
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