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PDGFB recombinant protein :: Platelet-derived growth factor subunit B (PDGFB) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1400854 PDGFB recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $560 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $745 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $820 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $870 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $970 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,085 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,090 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,105 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,155 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,580 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,650 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,685 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,115 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Platelet-derived growth factor subunit B (PDGFB), Recombinant Protein

 Also Known As   

Recombinant Dog Platelet-derived growth factor subunit B (PDGFB)

 Product Gene Name   

PDGFB recombinant protein

[Similar Products]
 Product Synonym Gene Name    PDGFB [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    82-242aa, Full Length of Mature Protein
 Sequence    SLGSPTVAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK KPTFKKATVT LEDHLACKCE TVVAARPVTR TPGSSQDLRA AKTPQTRVTI RTVRVRRPPK GKHRKFKHTH DKKALKETLG A
 3D Structure    ModBase 3D Structure for Q6Q7I7
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Canis familiaris (Dog) (Canis lupus familiaris)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PDGFB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for PDGFB recombinant protein

   This protein is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
NCBI/Uniprot data below describe general gene information for PDGFB. It may not necessarily be applicable to this product.
 NCBI GI #    50979258
 NCBI GeneID    442986
 NCBI Accession #    NP_001003383.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001003383.1 [Other Products]
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 UniProt Primary Accession #    Q6Q7I7 [Other Products]
 UniProt Related Accession #    Q6Q7I7 [Other Products]
 Molecular Weight    27,413 Da
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 NCBI Official Full Name    platelet-derived growth factor subunit B
 NCBI Official Synonym Full Names    platelet derived growth factor subunit B
 NCBI Official Symbol    PDGFB [Similar Products]
 NCBI Official Synonym Symbols   
PDGF-B
[Similar Products]
 NCBI Protein Information    platelet-derived growth factor subunit B
 UniProt Protein Name    Platelet-derived growth factor subunit B
 UniProt Synonym Protein Names   
PDGF-2; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide
 Protein Family    Platelet-derived growth factor
 UniProt Gene Name    PDGFB [Similar Products]
 UniProt Synonym Gene Names    PDGF subunit B [Similar Products]
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 UniProt Comments for PDGFB    Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA ().
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 Research Articles on PDGFB    1. The aim of this study was to investigate the role of PDGF-A, PDGF-B, PDGFR-alpha and PDGFR-beta in canine lymphoma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PDGFB recombinant proteinPathways associated with PDGFB recombinant protein
 Reference Product  PubMed Publications
 PDGFRB recombinant protein  >681 publications with PDGFB and PDGFRB
 PDGFRA recombinant protein  >357 publications with PDGFB and PDGFRA
 EGFR recombinant protein  >37 publications with PDGFB and EGFR
 PDGFA recombinant protein  >28 publications with PDGFB and PDGFA
 ERBB2 recombinant protein  >23 publications with PDGFB and ERBB2
 FGFR1 recombinant protein  >19 publications with PDGFB and FGFR1
 FGFR2 recombinant protein  >10 publications with PDGFB and FGFR2
 KDR recombinant protein  >10 publications with PDGFB and KDR
 FLT1 recombinant protein  >2 publications with PDGFB and FLT1
 FLT4 recombinant protein  >2 publications with PDGFB and FLT4
 Products by Pathway  Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Glioma Pathway antibodies  Glioma Pathway Diagram
 Glioma Pathway antibodies  Glioma Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with PDGFB recombinant proteinOrgans/Tissues associated with PDGFB recombinant protein
 Disease Name  Pubmed Publications
 Vascular Diseases Antibodies  >95 publications with PDGFB and Vascular Diseases
 Skin Neoplasms Antibodies  >84 publications with PDGFB and Skin Neoplasms
 Fibrosis Antibodies  >67 publications with PDGFB and Fibrosis
 Brain Diseases Antibodies  >56 publications with PDGFB and Brain Diseases
 Lung Diseases Antibodies  >53 publications with PDGFB and Lung Diseases
 Inflammation Antibodies  >51 publications with PDGFB and Inflammation
 Kidney Diseases Antibodies  >50 publications with PDGFB and Kidney Diseases
 Neoplasms, Experimental Antibodies  >48 publications with PDGFB and Neoplasms, Experimental
 Necrosis Antibodies  >44 publications with PDGFB and Necrosis
 Atherosclerosis Antibodies  >37 publications with PDGFB and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >169 publications with PDGFB and Muscle
 Brain Antibodies  >106 publications with PDGFB and Brain
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