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DDX5 recombinant protein :: Probable ATP-dependent RNA helicase DDX5 (DDX5) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS958623 DDX5 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $1,040 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,215 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,400 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,465 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,485 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,545 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,545 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,675 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,195 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,205 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,210 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,535 +3 FREE 8GB USB
1 mg (Baculovirus)  /  $2,895 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Probable ATP-dependent RNA helicase DDX5 (DDX5), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Probable ATP-dependent RNA helicase DDX5 (DDX5)

 Product Gene Name   

DDX5 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS958623 COA    COA PDF
 Sequence Positions    1-614aa, Full length protein
 Sequence    MSGYSSDRDR GRDRGFGAPR FGGSRAGPLS GKKFGNPGEK LVKKKWNLDE LPKFEKNFYQ EHPDLARRTA QEVETYRRSK EITVRGHNCP KPVLNFYEAN FPANVMDVIA RQNFTEPTAI QAQGWPVALS GLDMVGVAQT GSGKTLSYLL PAIVHINHQP FLERGDGPIC LVLAPTRELA QQVQQVAAEY CRACRLKSTC IYGGAPKGPQ IRDLERGVEI CIATPGRLID FLECGKTNLR RTTYLVLDEA DRMLDMGFEP QIRKIVDQIR PDRQTLMWSA TWPKEVRQLA EDFLKDYIHI NIGALELSAN HNILQIVDVC HDVEKDEKLI RLMEEIMSEK ENKTIVFVET KRRCDELTRK MRRDGWPAMG IHGDKSQQER DWVLNEFKHG KAPILIATDV ASRGLDVEDV KFVINYDYPN SSEDYIHRIG RTARSTKTGT AYTFFTPNNI KQVSDLISVL REANQAINPK LLQLVEDRGS GRSRGRGGMK DDRRDRYSAG KRGGFNTFRD RENYDRGYSS LLKRDFGAKT QNGVYSAANY TNGSFGSNFV SAGIQTSFRT GNPTGTYQNG YDSTQQYGSN VPNMHNGMNQ QAYAYPATAA APMIGYPMPT GYSQ
 OMIM    180630
 3D Structure    ModBase 3D Structure for P17844
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of DDX5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for DDX5 recombinant protein

   DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. This gene consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified.
NCBI/Uniprot data below describe general gene information for DDX5. It may not necessarily be applicable to this product.
 NCBI GI #    1002341719
 NCBI GeneID    1655
 NCBI Accession #    NP_001307524.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001320595.1 [Other Products]
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 UniProt Primary Accession #    P17844 [Other Products]
 UniProt Secondary Accession #    O75681; Q53Y61; B4DLW8; B5BU21; D3DU32; E7ETL9 [Other Products]
 UniProt Related Accession #    P17844 [Other Products]
 Molecular Weight    60,563 Da
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 NCBI Official Full Name    probable ATP-dependent RNA helicase DDX5 isoform a
 NCBI Official Synonym Full Names    DEAD-box helicase 5
 NCBI Official Symbol    DDX5 [Similar Products]
 NCBI Official Synonym Symbols   
p68; HLR1; G17P1; HUMP68
[Similar Products]
 NCBI Protein Information    probable ATP-dependent RNA helicase DDX5
 UniProt Protein Name    Probable ATP-dependent RNA helicase DDX5
 UniProt Synonym Protein Names   
DEAD box protein 5; RNA helicase p68
 Protein Family    Probable ATP-dependent RNA helicase
 UniProt Gene Name    DDX5 [Similar Products]
 UniProt Synonym Gene Names    G17P1; HELR; HLR1 [Similar Products]
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 NCBI Summary for DDX5    This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017]
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 UniProt Comments for DDX5    Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specific manner; the function probably involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms.
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 Research Articles on DDX5    1. Results show refined biochemical and biological comparison of yeast Dbp2 and human DDX5 enzymes. Human DDX5 possesses a 10-fold higher unwinding activity than Dbp2, partially due to the presence of a mammalian/avian specific C-terminal extension. Also, ectopic expression of DDX5 rescues the cold sensitivity, cryptic initiation defects, and impaired glucose import in dbp2Delta cells, suggesting functional conservation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DDX5 recombinant proteinPathways associated with DDX5 recombinant protein
 Reference Product  PubMed Publications
 DDX17 recombinant protein  >39 publications with DDX5 and DDX17
 DHX9 recombinant protein  >8 publications with DDX5 and DHX9
 RUNX2 recombinant protein  >3 publications with DDX5 and RUNX2
 Products by Pathway  Pathway Diagram
 Circadian Rythm Related Genes Pathway antibodies  Circadian Rythm Related Genes Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 Proteoglycans In Cancer Pathway antibodies  Proteoglycans In Cancer Pathway Diagram
 Proteoglycans In Cancer Pathway antibodies  Proteoglycans In Cancer Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
Diseases associated with DDX5 recombinant proteinOrgans/Tissues associated with DDX5 recombinant protein
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >19 publications with DDX5 and Carcinoma
 Nervous System Diseases Antibodies  >8 publications with DDX5 and Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >6 publications with DDX5 and Cell Transformation, Neoplastic
 Liver Diseases Antibodies  >5 publications with DDX5 and Liver Diseases
 Disease Models, Animal Antibodies  >4 publications with DDX5 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >4 publications with DDX5 and Neoplasm Metastasis
 Cardiovascular Diseases Antibodies  >4 publications with DDX5 and Cardiovascular Diseases
 Carcinoma, Hepatocellular Antibodies  >4 publications with DDX5 and Carcinoma, Hepatocellular
 Inflammation Antibodies  >4 publications with DDX5 and Inflammation
 Necrosis Antibodies  >4 publications with DDX5 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14 publications with DDX5 and Blood
 Liver Antibodies  >10 publications with DDX5 and Liver
 Kidney Antibodies  >7 publications with DDX5 and Kidney
 Muscle Antibodies  >7 publications with DDX5 and Muscle
 Bone Antibodies  >7 publications with DDX5 and Bone
 Prostate Antibodies  >7 publications with DDX5 and Prostate
 Lung Antibodies  >6 publications with DDX5 and Lung
 Vascular Antibodies  >5 publications with DDX5 and Vascular
 Embryonic Tissue Antibodies  >4 publications with DDX5 and Embryonic Tissue
 Connective Tissue Antibodies  >4 publications with DDX5 and Connective Tissue
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