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PCOLCE2 recombinant protein :: Procollagen C-endopeptidase enhancer 2 (PCOLCE2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1446879
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $910 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,040 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,225 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,290 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,320 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,385 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,900 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,955 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,110 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,505 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Procollagen C-endopeptidase enhancer 2 (PCOLCE2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Procollagen C-endopeptidase enhancer 2 (PCOLCE2)

 Product Synonym Names    Procollagen COOH-terminal proteinase enhancer 2; PCPE-2; Procollagen C-proteinase enhancer 2
 Product Gene Name   

PCOLCE2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1446879 COA    COA PDF
 Sequence Positions    24-415. Mature full length protein.
 Sequence    QSPERPVFTC GGILTGESGF IGSEGFPGVY PPNSKCTWKI TVPEGKVVVL NFRFIDLESD NLCRYDFVDV YNGHANGQRI GRFCGTFRPG ALVSSGNKMM VQMISDANTA GNGFMAMFSA AEPNERGDQY CGGLLDRPSG SFKTPNWPDR DYPAGVTCVW HIVAPKNQLI ELKFEKFDVE RDNYCRYDYV AVFNGGEVND ARRIGKYCGD SPPAPIVSER NELLIQFLSD LSLTADGFIG HYIFRPKKLP TTTEQPVTTT FPVTTGLKPT VALCQQKCRR TGTLEGNYCS SDFVLAGTVI TTITRDGSLH ATVSIINIYK EGNLAIQQAG KNMSARLTVV CKQCPLLRRG LNYIIMGQVG EDGRGKIMPN SFIMMFKTKN QKLLDALKNK QC
 OMIM    607064
 3D Structure    ModBase 3D Structure for Q9UKZ9
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PCOLCE2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for PCOLCE2 recombinant protein

   Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.
 Product Categories/Family for PCOLCE2 recombinant protein    Cell Biology
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 SDS-PAGE of PCOLCE2 recombinant protein    PCOLCE2 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for PCOLCE2. It may not necessarily be applicable to this product.
 NCBI GI #    7019483
 NCBI GeneID    26577
 NCBI Accession #    NP_037495.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_013363.3 [Other Products]
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 UniProt Primary Accession #    Q9UKZ9 [Other Products]
 UniProt Secondary Accession #    Q9BRH3; B2RCH9; D3DNG4 [Other Products]
 UniProt Related Accession #    Q9UKZ9 [Other Products]
 Molecular Weight    59.25kD
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 NCBI Official Full Name    procollagen C-endopeptidase enhancer 2
 NCBI Official Synonym Full Names    procollagen C-endopeptidase enhancer 2
 NCBI Official Symbol    PCOLCE2 [Similar Products]
 NCBI Official Synonym Symbols   
PCPE2
[Similar Products]
 NCBI Protein Information    procollagen C-endopeptidase enhancer 2
 UniProt Protein Name    Procollagen C-endopeptidase enhancer 2
 UniProt Synonym Protein Names   
Procollagen COOH-terminal proteinase enhancer 2; PCPE-2; Procollagen C-proteinase enhancer 2
 Protein Family    Procollagen C-endopeptidase enhancer
 UniProt Gene Name    PCOLCE2 [Similar Products]
 UniProt Synonym Gene Names    PCPE2; PCPE-2; Procollagen C-proteinase enhancer 2 [Similar Products]
 UniProt Entry Name    PCOC2_HUMAN
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 UniProt Comments for PCOLCE2    PCOLCE2: Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 3q21-q24

Molecular Function: collagen binding; heparin binding; protease activator activity
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Product References and Citations for PCOLCE2 recombinant protein

   "PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1." Steiglitz B.M., Keene D.R., Greenspan D.S. J. Biol. Chem. 277:49820-49830(2002)
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 Research Articles on PCOLCE2    1. Data indicate that PCPE2 accelerates the proteolytic processing of pro-apolipoprotein (apo) AI by enhancing the cleavage of the hexapeptide extension present at the N terminus of apoAI.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PCOLCE2 recombinant proteinPathways associated with PCOLCE2 recombinant protein
 Reference Product  PubMed Publications
 ADAMTS14 recombinant protein  >1 publications with PCOLCE2 and ADAMTS14
 ADAMTS2 recombinant protein  >1 publications with PCOLCE2 and ADAMTS2
 Products by Pathway  Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with PCOLCE2 recombinant proteinOrgans/Tissues associated with PCOLCE2 recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >3 publications with PCOLCE2 and Cardiovascular Diseases
 Neural Tube Defects Antibodies  >1 publications with PCOLCE2 and Neural Tube Defects
 Atrophy Antibodies  >1 publications with PCOLCE2 and Atrophy
 Hypertrophy Antibodies  >1 publications with PCOLCE2 and Hypertrophy
 Fibrosis Antibodies  >1 publications with PCOLCE2 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with PCOLCE2 and Blood
 Heart Antibodies  >5 publications with PCOLCE2 and Heart
 Bone Antibodies  >3 publications with PCOLCE2 and Bone
 Pancreas Antibodies  >2 publications with PCOLCE2 and Pancreas
 Embryonic Tissue Antibodies  >2 publications with PCOLCE2 and Embryonic Tissue
 Liver Antibodies  >1 publications with PCOLCE2 and Liver
 Thymus Antibodies  >1 publications with PCOLCE2 and Thymus
 Kidney Antibodies  >1 publications with PCOLCE2 and Kidney
 Brain Antibodies  >1 publications with PCOLCE2 and Brain
 Placenta Antibodies  >1 publications with PCOLCE2 and Placenta
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