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GNRH2 recombinant protein :: Progonadoliberin-2 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1014236
SDS-Page
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $660 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $820 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $895 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,000 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,030 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,055 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,495 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,520 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,615 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,005 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Progonadoliberin-2 (GNRH2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Progonadoliberin-2

 Product Synonym Names    Progonadoliberin II
 Product Gene Name   

GNRH2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    24-120aa; Full Length of Mature Protein
 Sequence    QHWSHGWYPG GKRALSSAQD PQNALRPPGR ALDTAAGSPV QTAHGLPSDA LAPLDDSMPW EGRTTAQWSL HRKRHLARTL LTAAREPRPA PPSSNKV
 OMIM    602352
 3D Structure    ModBase 3D Structure for O43555
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of GNRH2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for GNRH2 recombinant protein

   Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
 Product Categories/Family for GNRH2 recombinant protein    Signal Transduction
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 SDS-Page of GNRH2 recombinant protein    GNRH2 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for GNRH2. It may not necessarily be applicable to this product.
 NCBI GI #    872724315
 NCBI GeneID    2797
 NCBI Accession #    NP_001297149.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001310220.1 [Other Products]
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 UniProt Primary Accession #    O43555 [Other Products]
 UniProt Secondary Accession #    Q14C68; Q14C69; Q9BYN9; Q9BYP0 [Other Products]
 UniProt Related Accession #    O43555 [Other Products]
 Molecular Weight    26.5kD
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 NCBI Official Full Name    progonadoliberin-2 isoform a preproprotein
 NCBI Official Synonym Full Names    gonadotropin releasing hormone 2
 NCBI Official Symbol    GNRH2 [Similar Products]
 NCBI Official Synonym Symbols   
GnRH-II; LH-RHII
[Similar Products]
 NCBI Protein Information    progonadoliberin-2
 UniProt Protein Name    Progonadoliberin-2
 UniProt Synonym Protein Names   
Progonadoliberin II
 Protein Family    Progonadoliberin
 UniProt Gene Name    GNRH2 [Similar Products]
 UniProt Synonym Gene Names    GnRH II; LH-RH II [Similar Products]
 UniProt Entry Name    GON2_HUMAN
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 NCBI Summary for GNRH2    This gene encodes a secreted peptide hormone and member of the gonadotropin-releasing hormone (GnRH) family of proteins. The encoded protein regulates reproductive function by stimulating the production and release of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The encoded protein may inhibit endometrial, ovarian, prostate, and breast cancer cell proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
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 UniProt Comments for GNRH2    GNRH2: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. Belongs to the GnRH family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: multicellular organismal development; signal transduction
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Product References and Citations for GNRH2 recombinant protein

   Second gene for gonadotropin-releasing hormone in humans.White R.B., Eisen J.A., Kasten T.L., Fernald R.D.Proc. Natl. Acad. Sci. U.S.A. 95:305-309(1998) The DNA sequence and comparative analysis of human chromosome 20.Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.Nature 414:865-871(2001)
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 Research Articles on GNRH2    1. GnRHII expression correlated significantly with poor prognosis in breast cancer patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GNRH2 recombinant proteinPathways associated with GNRH2 recombinant protein
 Reference Product  PubMed Publications
 GNRH1 recombinant protein  >70 publications with GNRH2 and GNRH1
 KISS1 recombinant protein  >16 publications with GNRH2 and KISS1
 GNRHR recombinant protein  >9 publications with GNRH2 and GNRHR
 KISS1R recombinant protein  >5 publications with GNRH2 and KISS1R
 TAC3 recombinant protein  >1 publications with GNRH2 and TAC3
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 GnRH Signaling Pathway antibodies  GnRH Signaling Pathway Diagram
 GnRH Signaling Pathway antibodies  GnRH Signaling Pathway Diagram
 Hormone Ligand-binding Receptors Pathway antibodies  Hormone Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
Diseases associated with GNRH2 recombinant protein
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >2 publications with GNRH2 and Brain Diseases
 Liver Diseases Antibodies  >2 publications with GNRH2 and Liver Diseases
 Breast Neoplasms Antibodies  >1 publications with GNRH2 and Breast Neoplasms
 Hyperplasia Antibodies  >1 publications with GNRH2 and Hyperplasia
 Puberty, Precocious Antibodies  >1 publications with GNRH2 and Puberty, Precocious
 Embryo Loss Antibodies  >1 publications with GNRH2 and Embryo Loss
 Death Antibodies  >1 publications with GNRH2 and Death
 Infertility, Male Antibodies  >1 publications with GNRH2 and Infertility, Male
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