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PROM1 recombinant protein :: Prominin-1 (PROM1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1151261
SDS-Page
Unit / Price
0.01 mg (Yeast)  /  $110 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $190 +1 FREE 8GB USB
0.1 mg (Yeast)  /  $285 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $460 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $750 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Prominin-1 (PROM1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Prominin-1 (PROM1) , partial

 Product Gene Name   

PROM1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1151261 COA    COA PDF
 Sequence Positions    508-792. Partial, provide a fragment of the complete extracellular domain.
 Sequence    GANVEKLICE PYTSKELFRV LDTPYLLNED WEYYLSGKLF NKSKMKLTFE QVYSDCKKNR GTYGTLHLQN SFNISEHLNI NEHTGSISSE LESLKVNLNI FLLGAAGRKN LQDFAACGID RMNYDSYLAQ TGKSPAGVNL LSFAYDLEAK ANSLPPGNLR NSLKRDAQTI KTIHQQRVLP IEQSLSTLYQ SVKILQRTGN GLLERVTRIL ASLDFAQNFI TNNTSSVIIE ETKKYGRTII GYFEHYLQWI EFSISEKVAS CKPVATALDT AVDVFLCSYI IDPLN
 OMIM    603786
 3D Structure    ModBase 3D Structure for O43490
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PROM1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for PROM1 recombinant protein

   This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
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 SDS-Page of PROM1 recombinant protein    PROM1 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for PROM1. It may not necessarily be applicable to this product.
 NCBI GI #    224994189
 NCBI GeneID    8842
 NCBI Accession #    NP_001139319.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001145847.1 [Other Products]
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 UniProt Primary Accession #    O43490 [Other Products]
 UniProt Secondary Accession #    Q6SV49; Q6SV50; Q6SV51; Q6SV52; Q6SV53; Q96EN6 [Other Products]
 UniProt Related Accession #    O43490 [Other Products]
 Molecular Weight    94,605 Da
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 NCBI Official Full Name    prominin-1 isoform 2
 NCBI Official Synonym Full Names    prominin 1
 NCBI Official Symbol    PROM1 [Similar Products]
 NCBI Official Synonym Symbols   
RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
[Similar Products]
 NCBI Protein Information    prominin-1
 UniProt Protein Name    Prominin-1
 UniProt Synonym Protein Names   
Antigen AC133; Prominin-like protein 1; CD_antigen: CD133
 Protein Family    Prominin
 UniProt Gene Name    PROM1 [Similar Products]
 UniProt Synonym Gene Names    PROML1 [Similar Products]
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 NCBI Summary for PROM1    This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
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 UniProt Comments for PROM1    May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
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 Research Articles on PROM1    1. CD133+CD24lo phenotype defines 5-FU-resistant human colon cancer stem cell-like cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PROM1 recombinant proteinPathways associated with PROM1 recombinant protein
 Reference Product  PubMed Publications
 CD44 recombinant protein  >8 publications with PROM1 and CD44
 CD34 recombinant protein  >3 publications with PROM1 and CD34
 KDR recombinant protein  >2 publications with PROM1 and KDR
 HIF1A recombinant protein  >2 publications with PROM1 and HIF1A
 CDHR1 recombinant protein  >2 publications with PROM1 and CDHR1
 NES recombinant protein  >1 publications with PROM1 and NES
 RET recombinant protein  >1 publications with PROM1 and RET
 Products by Pathway  Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
Diseases associated with PROM1 recombinant proteinOrgans/Tissues associated with PROM1 recombinant protein
 Disease Name  Pubmed Publications
 Colorectal Neoplasms Antibodies  >12 publications with PROM1 and Colorectal Neoplasms
 Carcinoma Antibodies  >9 publications with PROM1 and Carcinoma
 Adenocarcinoma Antibodies  >6 publications with PROM1 and Adenocarcinoma
 Glioblastoma Antibodies  >6 publications with PROM1 and Glioblastoma
 Colonic Neoplasms Antibodies  >5 publications with PROM1 and Colonic Neoplasms
 Disease Models, Animal Antibodies  >5 publications with PROM1 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >4 publications with PROM1 and Neoplasm Metastasis
 Liver Neoplasms Antibodies  >3 publications with PROM1 and Liver Neoplasms
 Liver Diseases Antibodies  >3 publications with PROM1 and Liver Diseases
 Cell Transformation, Neoplastic Antibodies  >3 publications with PROM1 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >16 publications with PROM1 and Eye
 Brain Antibodies  >14 publications with PROM1 and Brain
 Liver Antibodies  >10 publications with PROM1 and Liver
 Nerve Antibodies  >5 publications with PROM1 and Nerve
 Intestine Antibodies  >4 publications with PROM1 and Intestine
 Embryonic Tissue Antibodies  >4 publications with PROM1 and Embryonic Tissue
 Lung Antibodies  >3 publications with PROM1 and Lung
 Stomach Antibodies  >2 publications with PROM1 and Stomach
 Testis Antibodies  >2 publications with PROM1 and Testis
 Mammary Gland Antibodies  >1 publications with PROM1 and Mammary Gland
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