NP_032849.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
properdin
NCBI Official Synonym Full Names
complement factor properdin
NCBI Official Synonym Symbols
NCBI Protein Information
properdin; complement factor P; properdin factor, complement
UniProt Protein Name
Properdin
UniProt Synonym Protein Names
Complement factor P
UniProt Synonym Gene Names
UniProt Entry Name
PROP_MOUSE
UniProt Comments for Cfp
CFP: A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Defects in CFP are the cause of properdin deficiency (PFD). PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
Protein type: Secreted; Secreted, signal peptide
Cellular Component: extracellular matrix; extracellular region
Biological Process: immune system process; complement activation, alternative pathway; innate immune response
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Pathways associated with Cfp recombinant protein
Diseases associated with Cfp recombinant protein
Organs/Tissues associated with Cfp recombinant protein
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