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Rln1 recombinant protein :: Prorelaxin 1 (Rln1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS955373
SDS-PAGE
Unit / Price
0.05 mg (E-Coli)  /  $425 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $565 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $610 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $615 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $770 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $820 +1 FREE 8GB USB
1 mg (E-Coli)  /  $870 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $930 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $975 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,005 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,400 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,410 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,540 +1 FREE 8GB USB
1 mg (Baculovirus)  /  $1,895 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Prorelaxin 1 (Rln1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rat Prorelaxin 1 (Rln1)

 Product Synonym Names    Recombinant Prorelaxin 1 (Rln1); Prorelaxin 1 Cleaved into the following 2 chains: 1. Relaxin B chain 2. Relaxin A chain
 Product Gene Name   

Rln1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Rln1; Rln [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    23-57aa; Cytoplasmic domain
 Sequence    RVSEEWMD QVIQVCGRGY ARAWIEVCGA SVGRLAL
 Chromosome Location    Chromosome: 1; NC_005100.3 (254731584..254734488, complement). Location: 1q52
 3D Structure    ModBase 3D Structure for P01347
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rattus norvegicus (Rat)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Rln1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Rln1 recombinant protein

   Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds; however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.
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 SDS-PAGE of Rln1 recombinant protein    Rat Prorelaxin 1 (Rln1)
No tagged;Tag removed (Additional charge required for tag removal service fee. Please inquire)
E.coli derived
Rln1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Rln1. It may not necessarily be applicable to this product.
 NCBI GI #    7242203
 NCBI GeneID    25616
 NCBI Accession #    NP_038199.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_013413.1 [Other Products]
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 UniProt Primary Accession #    P01347 [Other Products]
 UniProt Secondary Accession #    Q78N50 [Other Products]
 UniProt Related Accession #    P01347 [Other Products]
 Molecular Weight    20,489 Da [Similar Products]
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 NCBI Official Full Name    prorelaxin 1
 NCBI Official Synonym Full Names    relaxin 1
 NCBI Official Symbol    Rln1 [Similar Products]
 NCBI Official Synonym Symbols   
RELAX
[Similar Products]
 NCBI Protein Information    prorelaxin 1; preprorelaxin; Relaxin 1 (H1)
 UniProt Protein Name    Prorelaxin 1
 Protein Family    Prorelaxin
 UniProt Gene Name    Rln1 [Similar Products]
 UniProt Synonym Gene Names    Rln [Similar Products]
 UniProt Entry Name    REL1_RAT
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 NCBI Summary for Rln1    plays a role in pregnancy; involved in regulation of body fluid balance [RGD, Feb 2006]
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 UniProt Comments for Rln1    Function: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.

Subunit structure: Heterodimer of a B chain and an A chain linked by two disulfide bonds.

Subcellular location: Secreted.

Sequence similarities: Belongs to the insulin family.
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 Research Articles on Rln1    1. Data demonstrate a functional role for relaxin in mediating uterine artery compliance in pregnant rats, which may be necessary to maintain adequate uterine blood flow to the uterus and placenta.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Rln1 recombinant proteinDiseases associated with Rln1 recombinant protein
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Relaxin Receptors Pathway antibodies  Relaxin Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >10 publications with Rln1 and Fibrosis
 Neoplasms Antibodies  >5 publications with Rln1 and Neoplasms
 Heart Diseases Antibodies  >5 publications with Rln1 and Heart Diseases
 Cardiovascular Diseases Antibodies  >5 publications with Rln1 and Cardiovascular Diseases
 Hypertrophy Antibodies  >3 publications with Rln1 and Hypertrophy
 Prostatic Diseases Antibodies  >2 publications with Rln1 and Prostatic Diseases
 Adenocarcinoma Antibodies  >2 publications with Rln1 and Adenocarcinoma
 Disease Models, Animal Antibodies  >2 publications with Rln1 and Disease Models, Animal
 Musculoskeletal Diseases Antibodies  >1 publications with Rln1 and Musculoskeletal Diseases
 Prostatic Intraepithelial Neoplasia Antibodies  >1 publications with Rln1 and Prostatic Intraepithelial Neoplasia
Organs/Tissues associated with Rln1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >3 publications with Rln1 and Ovary
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