NP_032988.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,005 Da
NCBI Official Full Name
prostaglandin D2 receptor
NCBI Official Synonym Full Names
prostaglandin D receptor
NCBI Official Synonym Symbols
NCBI Protein Information
prostaglandin D2 receptor
UniProt Protein Name
Prostaglandin D2 receptor
UniProt Synonym Protein Names
Prostanoid DP receptor
UniProt Synonym Gene Names
UniProt Entry Name
PD2R_MOUSE
UniProt Comments for Ptgdr
PTGDR: Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate. Genetic variations in PTGDR are associated with susceptibility to asthma-related traits type 1 (ASRT1). Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass
Cellular Component: cytosol; integral to membrane; membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; prostaglandin D receptor activity; prostaglandin J receptor activity; signal transducer activity
Biological Process: adenosine metabolic process; G-protein coupled receptor protein signaling pathway; inflammatory response; male sex determination; signal transduction; sleep
Research Articles on Ptgdr
Precautions
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Disclaimer
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Pathways associated with Ptgdr recombinant protein
Diseases associated with Ptgdr recombinant protein
Organs/Tissues associated with Ptgdr recombinant protein
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