NP_694545.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
58,797 Da
NCBI Official Full Name
protein APCDD1
NCBI Official Synonym Full Names
APC down-regulated 1
NCBI Official Synonym Symbols
HHS; HTS; B7323; HYPT1; DRAPC1; FP7019 [Similar Products]
NCBI Protein Information
protein APCDD1
UniProt Protein Name
Protein APCDD1
UniProt Synonym Protein Names
Adenomatosis polyposis coli down-regulated 1 protein
NCBI Summary for APCDD1
This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.[provided by RefSeq, Sep 2010]
UniProt Comments for APCDD1
Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis.
Research Articles on APCDD1
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Disclaimer
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Products associated with APCDD1 recombinant protein
Diseases associated with APCDD1 recombinant protein
Organs/Tissues associated with APCDD1 recombinant protein
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