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PPP1R15A recombinant protein :: Protein phosphatase 1 regulatory subunit 15A (PPP1R15A) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1033254
SDS-PAGE
Unit / Price
0.01 mg (Yeast)  /  $135 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $255 +1 FREE 8GB USB
0.1 mg (Yeast)  /  $420 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $665 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $1,060 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,090 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,235 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,430 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,485 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,565 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,580 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,725 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,230 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,235 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,245 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,930 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Protein phosphatase 1 regulatory subunit 15A (PPP1R15A), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Protein phosphatase 1 regulatory subunit 15A (PPP1R15A)

 Product Gene Name   

PPP1R15A recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1033254 COA    COA PDF
 Sequence Positions    40-674aa, Full Length of Mature Protein
 Sequence    GPLEPWLVEA VKGAALVEAG LEGEARTPLA IPHTPWGRRP EEEAEDSGGP GEDRETLGLK TSSSLPEAWG LLDDDDGMYG EREATSVPRG QGSQFADGQR APLSPSLLIR TLQGSDKNPG EEKAEEEGVA EEEGVNKFSY PPSHRECCPA VEEEDDEEAV KKEAHRTSTS ALSPGSKPST WVSCPGEEEN QATEDKRTER SKGARKTSVS PRSSGSDPRS WEYRSGEASE EKEEKAHKET GKGEAAPGPQ SSAPAQRPQL KSWWCQPSDE EEGEVKALGA AEKDGEAECP PCIPPPSAFL KAWVYWPGED TEEEEDEEED EDSDSGSDEE EGEAEASSST PATGVFLKSW VYQPGEDTEE EEDEDSDTGS AEDEREAETS ASTPPASAFL KAWVYRPGED TEEEEDEDVD SEDKEDDSEA ALGEAESDPH PSHPDQRAHF RGWGYRPGKE TEEEEAAEDW GEAEPCPFRV AIYVPGEKPP PPWAPPRLPL RLQRRLKRPE TPTHDPDPET PLKARKVRFS EKVTVHFLAV WAGPAQAARQ GPWEQLARDR SRFARRITQA QEELSPCLTP AARARAWARL RNPPLAPIPA LTQTLPSSSV PSSPVQTTPL SQAVATPSRS SAAAAAALDL SGRRG
 OMIM    611048
 3D Structure    ModBase 3D Structure for O75807
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PPP1R15A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for PPP1R15A recombinant protein

   This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
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 SDS-PAGE of PPP1R15A recombinant protein    PPP1R15A recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for PPP1R15A. It may not necessarily be applicable to this product.
 NCBI GI #    157674363
 NCBI GeneID    23645
 NCBI Accession #    NP_055145.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_014330.3 [Other Products]
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 UniProt Primary Accession #    O75807 [Other Products]
 UniProt Secondary Accession #    Q6IA96; Q9NVU6; B4DKQ3 [Other Products]
 UniProt Related Accession #    O75807 [Other Products]
 Molecular Weight    56,515 Da
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 NCBI Official Full Name    protein phosphatase 1 regulatory subunit 15A
 NCBI Official Synonym Full Names    protein phosphatase 1 regulatory subunit 15A
 NCBI Official Symbol    PPP1R15A [Similar Products]
 NCBI Official Synonym Symbols   
GADD34
[Similar Products]
 NCBI Protein Information    protein phosphatase 1 regulatory subunit 15A
 UniProt Protein Name    Protein phosphatase 1 regulatory subunit 15A
 UniProt Synonym Protein Names   
Growth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116 homolog
 Protein Family    Protein phosphatase 1 regulatory
 UniProt Gene Name    PPP1R15A [Similar Products]
 UniProt Synonym Gene Names    GADD34 [Similar Products]
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 NCBI Summary for PPP1R15A    This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PPP1R15A    Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
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 Research Articles on PPP1R15A    1. Inhibition of IRE1 modifies the hypoxic regulation of GADD34 family gene expression in cultured glioma cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PPP1R15A recombinant proteinPathways associated with PPP1R15A recombinant protein
 Reference Product  PubMed Publications
 ATF4 recombinant protein  >24 publications with PPP1R15A and ATF4
 SMARCB1 recombinant protein  >3 publications with PPP1R15A and SMARCB1
 KIF3A recombinant protein  >1 publications with PPP1R15A and KIF3A
 SMAD7 recombinant protein  >1 publications with PPP1R15A and SMAD7
 Products by Pathway  Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downregulation Of TGF-beta Receptor Signaling Pathway antibodies  Downregulation Of TGF-beta Receptor Signaling Pathway Diagram
 Loss Of Function Of SMAD2/3 In Cancer Pathway antibodies  Loss Of Function Of SMAD2/3 In Cancer Pathway Diagram
 Loss Of Function Of SMAD4 In Cancer Pathway antibodies  Loss Of Function Of SMAD4 In Cancer Pathway Diagram
 Loss Of Function Of TGFBR1 In Cancer Pathway antibodies  Loss Of Function Of TGFBR1 In Cancer Pathway Diagram
 Loss Of Function Of TGFBR2 In Cancer Pathway antibodies  Loss Of Function Of TGFBR2 In Cancer Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 SMAD2/3 MH2 Domain Mutants In Cancer Pathway antibodies  SMAD2/3 MH2 Domain Mutants In Cancer Pathway Diagram
Diseases associated with PPP1R15A recombinant proteinOrgans/Tissues associated with PPP1R15A recombinant protein
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >17 publications with PPP1R15A and Necrosis
 Nervous System Diseases Antibodies  >15 publications with PPP1R15A and Nervous System Diseases
 Disease Models, Animal Antibodies  >14 publications with PPP1R15A and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >8 publications with PPP1R15A and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >7 publications with PPP1R15A and Neoplasms, Experimental
 Inflammation Antibodies  >6 publications with PPP1R15A and Inflammation
 Liver Diseases Antibodies  >6 publications with PPP1R15A and Liver Diseases
 Lung Neoplasms Antibodies  >3 publications with PPP1R15A and Lung Neoplasms
 Fatty Liver Antibodies  >3 publications with PPP1R15A and Fatty Liver
 Lung Diseases Antibodies  >3 publications with PPP1R15A and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17 publications with PPP1R15A and Blood
 Liver Antibodies  >14 publications with PPP1R15A and Liver
 Brain Antibodies  >14 publications with PPP1R15A and Brain
 Vascular Antibodies  >6 publications with PPP1R15A and Vascular
 Nerve Antibodies  >5 publications with PPP1R15A and Nerve
 Heart Antibodies  >5 publications with PPP1R15A and Heart
 Lung Antibodies  >5 publications with PPP1R15A and Lung
 Skin Antibodies  >4 publications with PPP1R15A and Skin
 Bone Antibodies  >4 publications with PPP1R15A and Bone
 Muscle Antibodies  >4 publications with PPP1R15A and Muscle
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