NP_723435.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
rolling stone
NCBI Official Synonym Full Names
rolling stone
NCBI Protein Information
CG9552 gene product from transcript CG9552-RA; CG9552-PA; rolling stone; rost-PA
UniProt Protein Name
Protein rolling stone
UniProt Entry Name
ROST_DROME
UniProt Comments for rost
Function: May have a central role in the fusion process during myogenesis, within the somatic mesoderm. Ref.1
Subcellular location: Membrane; Multi-pass membrane protein. Note: Enriched in the embryonic membrane fraction. Ref.1
Tissue specificity: Expressed in cells of the somatic mesoderm, most notably the muscle founder cells, between embryonic stages 12 and 14, in growing muscle fibers in dorsal, lateral and ventral positions. At stage 16 strongest expression is in some ventral muscles and muscle 8. At stages 16/17 expression is restricted to some cells of the CNS, the brain and the gonads. Ref.1
Developmental stage: Expressed both maternally and zygotically. High level of zygotic expression is seen in embryos from stage 12 onwards and in adults. Ref.1
Disruption phenotype: Flies exhibit diminished fusion of embryonic myoblasts to syncytial myotubes. Ref.1
Sequence caution: The sequence AAL28858.1 differs from that shown. Reason: Erroneous initiation.
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Diseases associated with rost recombinant protein
Organs/Tissues associated with rost recombinant protein
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