Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow Tgfa  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • dedicator of cytokinesis 8 (DOCK8) ELISA Kit
 • XRCC5 Antibody
 • CD171-N-CAML1 (Ab-1181) Antibody
 • DSS1 Antibody
 • Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2... Recombinant Protein
 • ELKS-RAB6-interacting-CAST family member 2 (ERC2) ELISA Kit
 • Insulin Antibody
 • Noradrenaline (NADR) ELISA Kit
 • clusterin Antibody
 • PVRL3 Antibody
 • FSH (BRD2) Antibody
 • TREM1 Antibody
 • tubby like protein 4 (TULP4) Antibody
 • Histamine H1 receptor (HRH1) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

Tgfa recombinant protein :: Protransforming growth factor alpha (Tgfa) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1191562 Tgfa recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $800 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $800 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,025 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,025 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,130 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,130 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,585 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,585 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Protransforming growth factor alpha (Tgfa), Recombinant Protein

 Also Known As   

Recombinant Rat Protransforming growth factor alpha (Tgfa)

 Product Synonym Names    Protransforming growth factor alphaCleaved into the following chain:; 1. Transforming growth factor alpha; 2. TGF-alpha; EGF-like TGF; ETGF; TGF type 1
 Product Gene Name   

Tgfa recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    24-97
 Sequence    ENSTSPL SDSPVAAAVV SHFNKCPDSH TQYCFHGTCR FLVQEEKPAC VCHSGYVGVR CEHADLLAVV AASQKKQ
 3D Structure    ModBase 3D Structure for P01134
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Rattus norvegicus (Rat)
Section Bar
 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Tgfa recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for Tgfa. It may not necessarily be applicable to this product.
 NCBI GI #    6981646
 NCBI GeneID    24827
 NCBI Accession #    NP_036803.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012671.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P01134 [Other Products]
 UniProt Secondary Accession #    Q63749 [Other Products]
 UniProt Related Accession #    P01134 [Other Products]
 Molecular Weight    16,960 Da
Table BarTOPTable Bar
 NCBI Official Full Name    protransforming growth factor alpha preproprotein
 NCBI Official Synonym Full Names    transforming growth factor alpha
 NCBI Official Symbol    Tgfa [Similar Products]
 NCBI Official Synonym Symbols   
TGFAA; RATTGFAA
[Similar Products]
 NCBI Protein Information    protransforming growth factor alpha
 UniProt Protein Name    Protransforming growth factor alpha
 UniProt Synonym Protein Names   
EGF-like TGF; ETGF; TGF type 1
 Protein Family    Protransforming growth factor
 UniProt Gene Name    Tgfa [Similar Products]
 UniProt Synonym Gene Names    TGF-alpha; ETGF [Similar Products]
 UniProt Entry Name    TGFA_RAT
Section Bar
 NCBI Summary for Tgfa    acts as an EGF receptor ligand; inhibits apoptosis that results from epithelial detachment from the extracellular matrix [RGD, Feb 2006]
Section Bar
 UniProt Comments for Tgfa    TGFalpha: TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. Interacts with the PDZ domains of MAGI3, SDCBP and SNTA1. The interaction with SDCBP, is required for the targeting to the cell surface. In the endoplasmic reticulum, in its immature form (i.e. with a prosegment and lacking full N-glycosylation), interacts with CNIH. In the Golgi apparatus, may form a complex with CNIH and GORASP2. Interacts (via cytoplasmic C-terminal domain) with NKD2. Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Ligand, receptor tyrosine kinase; Cell cycle regulation

Cellular Component: extracellular space; cell surface; integral to plasma membrane; basolateral plasma membrane; perinuclear region of cytoplasm; plasma membrane; cytoplasmic vesicle; nucleus

Molecular Function: growth factor activity; glycoprotein binding; epidermal growth factor receptor binding

Biological Process: response to drug; epidermal growth factor receptor signaling pathway; negative regulation of cellular process; wound healing; positive regulation of epidermal growth factor receptor activity; positive regulation of mitosis; activation of MAPK activity; positive regulation of cell proliferation; angiogenesis; positive regulation of epithelial cell proliferation; negative regulation of apoptosis
Table BarTOPTable Bar
 Research Articles on Tgfa    1. mechanical stretch promotes fetal type II cell differentiation via ectodomain shedding of HB-EGF and TGF-alpha
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with Tgfa recombinant proteinPathways associated with Tgfa recombinant protein
 Reference Product  PubMed Publications
 Egfr recombinant protein  >35 publications with Tgfa and Egfr
 Erbb2 recombinant protein  >7 publications with Tgfa and Erbb2
 Fgfr1 recombinant protein  >5 publications with Tgfa and Fgfr1
 Erbb4 recombinant protein  >3 publications with Tgfa and Erbb4
 Pdgfra recombinant protein  >3 publications with Tgfa and Pdgfra
 Erbb3 recombinant protein  >2 publications with Tgfa and Erbb3
 Pdgfrb recombinant protein  >2 publications with Tgfa and Pdgfrb
 Igf1r recombinant protein  >1 publications with Tgfa and Igf1r
 Fgfr2 recombinant protein  >1 publications with Tgfa and Fgfr2
 Products by Pathway  Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram
 Glioma Pathway antibodies  Glioma Pathway Diagram
 Glioma Pathway antibodies  Glioma Pathway Diagram
 Non-small Cell Lung Cancer Pathway antibodies  Non-small Cell Lung Cancer Pathway Diagram
 Non-small Cell Lung Cancer Pathway antibodies  Non-small Cell Lung Cancer Pathway Diagram
 Pancreatic Cancer Pathway antibodies  Pancreatic Cancer Pathway Diagram
 Pancreatic Cancer Pathway antibodies  Pancreatic Cancer Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
Diseases associated with Tgfa recombinant proteinOrgans/Tissues associated with Tgfa recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >63 publications with Tgfa and Neoplasms
 Genetic Predisposition to Disease Antibodies  >17 publications with Tgfa and Genetic Predisposition to Disease
 Fatty Liver Antibodies  >16 publications with Tgfa and Fatty Liver
 Liver Diseases Antibodies  >10 publications with Tgfa and Liver Diseases
 Liver Neoplasms Antibodies  >10 publications with Tgfa and Liver Neoplasms
 Head and Neck Neoplasms Antibodies  >9 publications with Tgfa and Head and Neck Neoplasms
 Breast Neoplasms Antibodies  >9 publications with Tgfa and Breast Neoplasms
 Inflammation Antibodies  >7 publications with Tgfa and Inflammation
 Neoplasms, Experimental Antibodies  >7 publications with Tgfa and Neoplasms, Experimental
 Nervous System Diseases Antibodies  >7 publications with Tgfa and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >17 publications with Tgfa and Connective Tissue
 Prostate Antibodies  >8 publications with Tgfa and Prostate
 Ovary Antibodies  >4 publications with Tgfa and Ovary
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions