WP_004218911.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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Molecular Weight
55,439 Da
NCBI Official Full Name
Pup--protein ligase
UniProt Protein Name
Pup--protein ligase
UniProt Synonym Protein Names
Proteasome accessory factor A
UniProt Comments for pafA
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
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