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NOP2 recombinant protein :: Putative ribosomal RNA methyltransferase NOP2 (NOP2), partial Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS962347 NOP2 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $835 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $835 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,055 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,055 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,170 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,170 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,620 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,620 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Putative ribosomal RNA methyltransferase NOP2 (NOP2), partial, Recombinant Protein

 Also Known As   

Recombinant Human Putative ribosomal RNA methyltransferase NOP2 (NOP2), partial

 Product Synonym Names    Putative ribosomal RNA methyltransferase NOP2; EC=2.1.1.-; Nucleolar protein 1; Nucleolar protein 2 homolog; Proliferating-cell nucleolar antigen p120; Proliferation-associated nucleolar protein p120
 Product Gene Name   

NOP2 recombinant protein

[Similar Products]
 Product Synonym Gene Name    NOP2; NOL1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    164031
 3D Structure    ModBase 3D Structure for P46087
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of NOP2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for NOP2. It may not necessarily be applicable to this product.
 NCBI GI #    76150625
 NCBI GeneID    4839
 NCBI Accession #    NP_001028886.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001033714.2 [Other Products]
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 UniProt Primary Accession #    P46087 [Other Products]
 UniProt Secondary Accession #    Q05BA7; Q0P5S5; Q3KQS4; Q58F30; A1A4Z3; B3KPD6 [Other Products]
 UniProt Related Accession #    P46087 [Other Products]
 Molecular Weight    92,860 Da
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 NCBI Official Full Name    putative ribosomal RNA methyltransferase NOP2 isoform 1
 NCBI Official Synonym Full Names    NOP2 nucleolar protein
 NCBI Official Symbol    NOP2 [Similar Products]
 NCBI Official Synonym Symbols   
NOL1; p120; NSUN1; NOP120
[Similar Products]
 NCBI Protein Information    putative ribosomal RNA methyltransferase NOP2; nucleolar protein 1, 120kDa; nucleolar protein 2 homolog; NOP2 nucleolar protein homolog; NOL1/NOP2/Sun domain family, member 1; proliferating-cell nucleolar antigen p120; proliferation-associated nucleolar protein p120
 UniProt Protein Name    Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase
 UniProt Synonym Protein Names   
Nucleolar protein 1; Nucleolar protein 2 homolog; Proliferating-cell nucleolar antigen p120; Proliferation-associated nucleolar protein p120
 Protein Family    Probable 28S rRNA
 UniProt Gene Name    NOP2 [Similar Products]
 UniProt Synonym Gene Names    NOL1; NSUN1 [Similar Products]
 UniProt Entry Name    NOP2_HUMAN
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 UniProt Comments for NOP2    NOP2: May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase. Belongs to the methyltransferase superfamily. RsmB/NOP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Methyltransferase; RNA-binding; Nucleolus; Cell cycle regulation; EC 2.1.1.-

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: nucleolus

Molecular Function: protein binding; S-adenosylmethionine-dependent methyltransferase activity

Biological Process: methylation; positive regulation of cell proliferation; rRNA processing
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NOP2 recombinant proteinDiseases associated with NOP2 recombinant protein
 Reference Product  PubMed Publications
 NIP7 recombinant protein  >1 publications with NOP2 and NIP7
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >12 publications with NOP2 and Breast Neoplasms
 Nervous System Diseases Antibodies  >5 publications with NOP2 and Nervous System Diseases
 Prostatic Diseases Antibodies  >5 publications with NOP2 and Prostatic Diseases
 Hyperplasia Antibodies  >4 publications with NOP2 and Hyperplasia
 Liver Neoplasms, Experimental Antibodies  >3 publications with NOP2 and Liver Neoplasms, Experimental
 Congenital, Hereditary, and Neonatal Diseases and Abnormalities Antibodies  >2 publications with NOP2 and Congenital, Hereditary, and Neonatal Diseases and Abnormalities
 Carcinoma, Hepatocellular Antibodies  >2 publications with NOP2 and Carcinoma, Hepatocellular
 Congenital Abnormalities Antibodies  >2 publications with NOP2 and Congenital Abnormalities
 Necrosis Antibodies  >2 publications with NOP2 and Necrosis
 Ovarian Diseases Antibodies  >1 publications with NOP2 and Ovarian Diseases
Organs/Tissues associated with NOP2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >11 publications with NOP2 and Blood
 Prostate Antibodies  >7 publications with NOP2 and Prostate
 Lung Antibodies  >7 publications with NOP2 and Lung
 Liver Antibodies  >5 publications with NOP2 and Liver
 Lymph Antibodies  >3 publications with NOP2 and Lymph
 Bone Antibodies  >3 publications with NOP2 and Bone
 Bone Marrow Antibodies  >3 publications with NOP2 and Bone Marrow
 Lymph Node Antibodies  >3 publications with NOP2 and Lymph Node
 Mouth Antibodies  >3 publications with NOP2 and Mouth
 Bladder Antibodies  >2 publications with NOP2 and Bladder
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