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PDC1 recombinant protein :: Pyruvate decarboxylase isozyme 1 (PDC1), partial Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1235110 PDC1 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $900 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $900 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,125 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,125 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,275 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,275 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,735 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,735 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,770 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,510 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Pyruvate decarboxylase isozyme 1 (PDC1), partial, Recombinant Protein

 Also Known As   

Recombinant Saccharomyces cerevisiae Pyruvate decarboxylase isozyme 1 (PDC1), partial

 Product Synonym Names    Pyruvate decarboxylase isozyme 1; EC=4.1.1.-; EC=4.1.1.1
 Product Gene Name   

PDC1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    PDC1; YLR044C; L2104 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    191-320; Partial.
 Sequence    PNDAESEKEV IDTILALVKD AKNPVILADA CCSRHDVKAE TKKLIDLTQF PAFVTPMGKG SIDEQHPRYG GVYVGTLSKP EVKEAVESAD LILSVGALLS DFNTGSFSYS YKTKNIVEFH SDHMKIRNAT
 3D Structure    ModBase 3D Structure for P06169
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PDC1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for PDC1. It may not necessarily be applicable to this product.
 NCBI GI #    6323073
 NCBI GeneID    850733
 NCBI Accession #    NP_013145.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001181931.1 [Other Products]
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 UniProt Primary Accession #    P06169 [Other Products]
 UniProt Secondary Accession #    O00042; Q07991; Q12682; Q12686; Q12687; D6VY46 [Other Products]
 UniProt Related Accession #    P06169 [Other Products]
 Molecular Weight    61,495 Da
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 NCBI Official Full Name    indolepyruvate decarboxylase 1
 NCBI Official Symbol    PDC1 [Similar Products]
 NCBI Protein Information    indolepyruvate decarboxylase 1
 UniProt Protein Name    Pyruvate decarboxylase isozyme 1
 Protein Family    Pyruvate decarboxylase
 UniProt Gene Name    PDC1 [Similar Products]
 UniProt Entry Name    PDC1_YEAST
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 UniProt Comments for PDC1    Major of three pyruvate decarboxylases (PDC1, PDC5, PDC6) implicated in the nonoxidative conversion of pyruvate to acetaldehyde and carbon dioxide during alcoholic fermentation. Most of the produced acetaldehyde is subsequently reduced to ethanol, but some is required for cytosolic acetyl-CoA production for biosynthetic pathways. The enzyme is also one of five 2-oxo acid decarboxylases (PDC1, PDC5, PDC6, ARO10, and THI3) able to decarboxylate more complex 2-oxo acids (alpha-ketoacids) than pyruvate, which seem mainly involved in amino acid catabolism. Here the enzyme catalyzes the decarboxylation of amino acids, which, in a first step, have been transaminated to the corresponding 2-oxo acids. In a third step, the resulting aldehydes are reduced to alcohols, collectively referred to as fusel oils or alcohols. Its preferred substrates are the transaminated amino acids valine, isoleucine, phenylalanine, and tryptophan, whereas leucine is no substrate. In a side-reaction the carbanionic intermediate (or active aldehyde) generated by decarboxylation or by activation of an aldehyde can react with an aldehyde via condensation (or carboligation) yielding a 2-hydroxy ketone, collectively called acyloins.
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 Research Articles on PDC1    1. These results suggest that the Pdc1p phosphorylation dependent on SIT4 occurs at residues that change the apparent affinity for thiamine pyrophosphate and pyruvate.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PDC1 recombinant protein
 Products by Pathway  Pathway Diagram
 Biosynthesis Of Secondary Metabolites Pathway antibodies  Biosynthesis Of Secondary Metabolites Pathway Diagram
 Glucose Fermentation Pathway antibodies  Glucose Fermentation Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Glycolysis And Gluconeogenesis Pathway antibodies  Glycolysis And Gluconeogenesis Pathway Diagram
 Isoleucine Degradation Pathway antibodies  Isoleucine Degradation Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Phenylalanine Degradation Pathway antibodies  Phenylalanine Degradation Pathway Diagram
 Principle Pathways Of Carbon Metabolism antibodies  Principle Pathways Of Carbon Metabolism Diagram
 Tryptophan Degradation Pathway antibodies  Tryptophan Degradation Pathway Diagram
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