Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource rightarrow Recombinant Protein rightarrow PDC1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • tumor necrosis factor receptor superfamily, member 11a, NFKB... ELISA Kit
 • COX5B Antibody
 • PKC Gamma (PRKCG) Antibody
 • Thrombin ELISA Kit
 • Desmoglein-3 (Dsg3) Recombinant Protein
 • ASAH1 Antibody
 • GABAB R1 Antibody
 • T-box transcription factor TBX18 (Tbx18) Recombinant Protein
 • Low Density Lipoprotein Receptor-Related Protein (LRP) (85kD... Antibody
 • S100 Calcium Binding Protein A12 (S100A12) ELISA Kit
 • Cross-Linked C-Terminal Telopeptides of Type I Collagen (ICT... ELISA Kit
 • WAVE1 (N-terminal region) Peptide (WASF1) Peptide
 • cardiotrophin 1 (CTF1) ELISA Kit
 downarrow more ...
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

PDC1 recombinant protein :: Pyruvate decarboxylase isozyme 1 (PDC1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1235110 PDC1 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $900 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $900 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,125 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,125 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,275 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,275 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,735 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,735 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,770 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,510 +3 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Pyruvate decarboxylase isozyme 1 (PDC1), Recombinant Protein

 Also Known As   

Recombinant Saccharomyces cerevisiae Pyruvate decarboxylase isozyme 1 (PDC1) , partial

 Product Gene Name   

PDC1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    191-320; Partial.
 3D Structure    ModBase 3D Structure for P06169
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
Section Bar
 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PDC1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PDC1. It may not necessarily be applicable to this product.
 NCBI GI #    6323073
 NCBI GeneID    850733
 NCBI Accession #    NP_013145.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001181931.1 [Other Products]
Section Bar
 UniProt Primary Accession #    P06169 [Other Products]
 UniProt Secondary Accession #    O00042; Q07991; Q12682; Q12686; Q12687; D6VY46 [Other Products]
 UniProt Related Accession #    P06169 [Other Products]
 Molecular Weight    61,495 Da
Table BarTOPTable Bar
 NCBI Official Full Name    indolepyruvate decarboxylase 1
 NCBI Official Symbol    PDC1 [Similar Products]
 NCBI Protein Information    indolepyruvate decarboxylase 1
 UniProt Protein Name    Pyruvate decarboxylase isozyme 1
 UniProt Synonym Protein Names   
Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC
 Protein Family    Pyruvate decarboxylase
 UniProt Gene Name    PDC1 [Similar Products]
 UniProt Synonym Gene Names    2ODC [Similar Products]
Section Bar
 UniProt Comments for PDC1    Major of three pyruvate decarboxylases (PDC1, PDC5, PDC6) implicated in the nonoxidative conversion of pyruvate to acetaldehyde and carbon dioxide during alcoholic fermentation. Most of the produced acetaldehyde is subsequently reduced to ethanol, but some is required for cytosolic acetyl-CoA production for biosynthetic pathways. The enzyme is also one of five 2-oxo acid decarboxylases (PDC1, PDC5, PDC6, ARO10, and THI3) able to decarboxylate more complex 2-oxo acids (alpha-ketoacids) than pyruvate, which seem mainly involved in amino acid catabolism. Here the enzyme catalyzes the decarboxylation of amino acids, which, in a first step, have been transaminated to the corresponding 2-oxo acids. In a third step, the resulting aldehydes are reduced to alcohols, collectively referred to as fusel oils or alcohols. Its preferred substrates are the transaminated amino acids derived from threonine (2-oxobutanoate), norvaline (2-oxopentanoate), valine (3-methyl-2-oxobutanoate, also alpha-keto-isovalerate), isoleucine ((3S)-3-methyl-2-oxopentanoate, also alpha-keto-beta-methylvalerate), phenylalanine (phenylpyruvate), and tryptophan (3-(indol-3-yl)pyruvate), whereas transaminated leucine is no substrate. In a side-reaction the carbanionic intermediate (or active aldehyde) generated by decarboxylation or by activation of an aldehyde can react with an aldehyde via condensation (or carboligation) yielding a 2-hydroxy ketone, collectively called acyloins.
Table BarTOPTable Bar
 Research Articles on PDC1    1. These results suggest that the Pdc1p phosphorylation dependent on SIT4 occurs at residues that change the apparent affinity for thiamine pyrophosphate and pyruvate.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with PDC1 recombinant protein
 Products by Pathway  Pathway Diagram
 Biosynthesis Of Secondary Metabolites Pathway antibodies  Biosynthesis Of Secondary Metabolites Pathway Diagram
 Glucose Fermentation Pathway antibodies  Glucose Fermentation Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Glycolysis And Gluconeogenesis Pathway antibodies  Glycolysis And Gluconeogenesis Pathway Diagram
 Isoleucine Degradation Pathway antibodies  Isoleucine Degradation Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Phenylalanine Degradation Pathway antibodies  Phenylalanine Degradation Pathway Diagram
 Principle Pathways Of Carbon Metabolism antibodies  Principle Pathways Of Carbon Metabolism Diagram
 Tryptophan Degradation Pathway antibodies  Tryptophan Degradation Pathway Diagram
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions