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Gorab recombinant protein :: RAB6-interacting golgin (Gorab) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1341281 Gorab recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $780 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $890 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,025 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,040 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,150 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,200 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,270 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,300 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,355 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,630 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,870 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,925 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,060 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,480 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RAB6-interacting golgin (Gorab), Recombinant Protein

 Also Known As   

Recombinant Mouse RAB6-interacting golgin (Gorab)

 Product Synonym Names    RAB6-interacting golgin; N-terminal kinase-like-binding protein 1; NTKL-BP1; NTKL-binding protein 1; mNTKL-BP1; SCY1-like 1-binding protein 1; SCYL1-BP1; SCYL1-binding protein 1
 Product Gene Name   

Gorab recombinant protein

[Similar Products]
 Product Synonym Gene Name    Gorab; Ntklbp1; Scyl1bp1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-368aa; full length protein
 Sequence    MAQDWAGFSE EELRRLKQNK DPFEPQRRIP VKKTRQQLQR EKALLEQSQK LGLQDGSASL LPEQLLSAPK QRANSQKPRS PSPVAPSPLT PTSSSGDGKL PGVGSQPQEP GLENSHHGHK SAEVRAPKPD CKVEKKKMEL QEKSRWEVLQ QEQRLMEEKN KRKKALLAQA IAERSKKTQA ETIKLKRIQK ELQALDDMVS ADIGILRNRI DQASLEYSYA RKRFDRAEAE YITAKLDLQR KTETKEQLTE HLCTIIQQNE LRKAKKLEEL MQQLDVQADE EALQLEVEVE QLLREQEAEA AKQMASVERL CPPDGESVSS ELAEENNEPQ KQAPSPETDK PGKCCSSSPH RLDCPDPGAK NFSAAVAT
 3D Structure    ModBase 3D Structure for Q8BRM2
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Gorab recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Gorab recombinant protein

   This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described.
NCBI/Uniprot data below describe general gene information for Gorab. It may not necessarily be applicable to this product.
 NCBI GI #    31559831
 NCBI GeneID    98376
 NCBI Accession #    NP_849214.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_178883.5 [Other Products]
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 UniProt Primary Accession #    Q8BRM2 [Other Products]
 UniProt Secondary Accession #    Q8CAA8 [Other Products]
 UniProt Related Accession #    Q8BRM2 [Other Products]
 Molecular Weight    24,078 Da
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 NCBI Official Full Name    RAB6-interacting golgin
 NCBI Official Synonym Full Names    golgin, RAB6-interacting
 NCBI Official Symbol    Gorab [Similar Products]
 NCBI Official Synonym Symbols   
AI467484; NTKL-BP1; Scyl1bp1
[Similar Products]
 NCBI Protein Information    RAB6-interacting golgin; SCYL1-BP1; mNTKL-BP1; NTKL-binding protein 1; SCYL1-binding protein 1; SCY1-like 1 binding protein 1; SCY1-like 1-binding protein 1; N-terminal kinase-like-binding protein 1; dynactin 1, isoform 1; dynactin 1 (p150, Glued homolog); p150, Glued homolog; 150 kDa dynein-associated polypeptide; p150-glued
 UniProt Protein Name    RAB6-interacting golgin
 UniProt Synonym Protein Names   
N-terminal kinase-like-binding protein 1; NTKL-BP1; NTKL-binding protein 1; mNTKL-BP1; SCY1-like 1-binding protein 1; SCYL1-BP1; SCYL1-binding protein 1
 Protein Family    RAB6-interacting golgin
 UniProt Gene Name    Gorab [Similar Products]
 UniProt Synonym Gene Names    Ntklbp1; Scyl1bp1; NTKL-BP1; NTKL-binding protein 1; mNTKL-BP1; SCYL1-BP1; SCYL1-binding protein 1 [Similar Products]
 UniProt Entry Name    GORAB_MOUSE
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 UniProt Comments for Gorab    SCYL1BP1: Defects in GORAB are the cause of geroderma osteodysplasticum (GO); also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation. Belongs to the GORAB family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; nucleolus; nucleus

Molecular Function: protein binding
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 Research Articles on Gorab    1. The G59S mutation in p150(glued) protein abrogates the normal function of the protein and accelerates motor neuron degeneration.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with Gorab recombinant proteinOrgans/Tissues associated with Gorab recombinant protein
 Disease Name  Pubmed Publications
 Musculoskeletal Diseases Antibodies  >6 publications with Gorab and Musculoskeletal Diseases
 Skin Abnormalities Antibodies  >2 publications with Gorab and Skin Abnormalities
 Ureteral Obstruction Antibodies  >1 publications with Gorab and Ureteral Obstruction
 Cardiovascular Diseases Antibodies  >1 publications with Gorab and Cardiovascular Diseases
 Kidney Diseases Antibodies  >1 publications with Gorab and Kidney Diseases
 Breast Neoplasms Antibodies  >1 publications with Gorab and Breast Neoplasms
 Congenital Abnormalities Antibodies  >1 publications with Gorab and Congenital Abnormalities
 Gerodermia osteodysplastica Antibodies  >1 publications with Gorab and Gerodermia osteodysplastica
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >8 publications with Gorab and Bone
 Skin Antibodies  >3 publications with Gorab and Skin
 Kidney Antibodies  >1 publications with Gorab and Kidney
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