Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow RBM25  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • MEF2C Antibody
 • Thermolysin Antibody
 • gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2) ELISA Kit
 • RFX5 Antibody
 • serpin peptidase inhibitor, clade I (pancpin) , member 2 (SE... ELISA Kit
 • Oocyte-expressed protein homolog (OOEP) Recombinant Protein
 • IL32 Antibody
 • hyaluronan synthase 2 (HAS2) ELISA Kit
 • TSPY-like 2 (TSPYL2) Antibody
 • Fatty Acid Binding Protein (h-FABP) Protein
 • Apolipoprotein AI (Apo AI) (APOA1) Antibody
 • Human IgG protein (Fab) (FITC) Immunoglobulin
 • Aspa Antibody
 • CIKS (TRAF3IP2) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

RBM25 recombinant protein :: RNA-binding protein 25 (RBM25), partial Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS959509 RBM25 recombinant protein
Unit / Price
 Please Inquire 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RNA-binding protein 25 (RBM25), partial, Recombinant Protein

 Also Known As   

Recombinant Human RNA-binding protein 25 (RBM25), partial

 Product Synonym Names    RNA-binding protein 25; Arg/Glu/Asp-rich protein of 120 kDa; RED120; Protein S164; RNA-binding motif protein 25; RNA-binding region-containing protein 7
 Product Gene Name   

RBM25 recombinant protein

[Similar Products]
 Product Synonym Gene Name    RBM25; RNPC7 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    612427
 3D Structure    ModBase 3D Structure for P49756
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Homo sapiens (Human)
Section Bar
 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of RBM25 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for RBM25. It may not necessarily be applicable to this product.
 NCBI GI #    55741709
 NCBI GeneID    58517
 NCBI Accession #    NP_067062.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021239.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P49756 [Other Products]
 UniProt Secondary Accession #    Q2TA72; Q5XJ17; Q6P665; Q9H6A1; Q9UEQ5; Q9UIE9; A0PJL9; B2RNA8; B3KT03 [Other Products]
 UniProt Related Accession #    P49756 [Other Products]
 Molecular Weight    17,953 Da
Table BarTOPTable Bar
 NCBI Official Full Name    RNA-binding protein 25
 NCBI Official Synonym Full Names    RNA binding motif protein 25
 NCBI Official Symbol    RBM25 [Similar Products]
 NCBI Official Synonym Symbols   
S164; NET52; RNPC7; Snu71; RED120; fSAP94
[Similar Products]
 NCBI Protein Information    RNA-binding protein 25; RNA-binding motif protein 25; Arg/Glu/Asp-rich protein, 120 kDa; arg/Glu/Asp-rich protein of 120 kDa; RNA-binding region-containing protein 7; RNA-binding region (RNP1, RRM) containing 7; functional spliceosome-associated protein 94; U1 small nuclear ribonucleoprotein 1SNRP homolog
 UniProt Protein Name    RNA-binding protein 25
 UniProt Synonym Protein Names   
Arg/Glu/Asp-rich protein of 120 kDa; RED120; Protein S164; RNA-binding motif protein 25; RNA-binding region-containing protein 7
 Protein Family    RNA-binding protein
 UniProt Gene Name    RBM25 [Similar Products]
 UniProt Synonym Gene Names    RNPC7; RED120 [Similar Products]
 UniProt Entry Name    RBM25_HUMAN
Section Bar
 UniProt Comments for RBM25    RBM25: RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: nucleoplasm; spliceosome; cytoplasm; nuclear speck

Molecular Function: mRNA binding; protein binding; nucleotide binding

Biological Process: regulation of apoptosis; RNA splicing; mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome
Table BarTOPTable Bar
 Research Articles on RBM25    1. Structure-guided mutagenesis reveals a positively charged nucleic-acid-binding surface in the RBM25 PWI domain
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with RBM25 recombinant proteinDiseases associated with RBM25 recombinant protein
 Products by Pathway  Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >2 publications with RBM25 and Heart Diseases
 Liver Diseases Antibodies  >2 publications with RBM25 and Liver Diseases
 Poisoning Antibodies  >1 publications with RBM25 and Poisoning
Organs/Tissues associated with RBM25 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >3 publications with RBM25 and Bone
 Bone Marrow Antibodies  >3 publications with RBM25 and Bone Marrow
 Liver Antibodies  >3 publications with RBM25 and Liver
 Heart Antibodies  >2 publications with RBM25 and Heart
 Pancreas Antibodies  >1 publications with RBM25 and Pancreas
 Muscle Antibodies  >1 publications with RBM25 and Muscle
 Embryonic Tissue Antibodies  >1 publications with RBM25 and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions