NP_001185878.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
75,043 Da
NCBI Official Full Name
ralA-binding protein 1
NCBI Official Synonym Full Names
ralA binding protein 1
NCBI Official Synonym Symbols
NCBI Protein Information
ralA-binding protein 1
UniProt Protein Name
RalA-binding protein 1
UniProt Synonym Protein Names
Dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; Ral-interacting protein 1
UniProt Synonym Gene Names
UniProt Comments for Ralbp1
Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin ().
Research Articles on Ralbp1
Precautions
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Disclaimer
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Pathways associated with Ralbp1 recombinant protein
Diseases associated with Ralbp1 recombinant protein
Organs/Tissues associated with Ralbp1 recombinant protein
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