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Rab10 recombinant protein :: Ras-related protein Rab-10 (Rab10) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS960891
SDS-Page
Unit / Price
0.05 mg (E-Coli)  /  $600 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $750 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $800 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $885 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $900 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,005 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,130 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,140 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,140 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,245 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,635 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,725 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,730 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,185 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ras-related protein Rab-10 (Rab10), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Ras-related protein Rab-10 (Rab10)

 Product Synonym Names    Ras-related protein Rab-10
 Product Gene Name   

Rab10 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS960891 COA    COA PDF
 Sequence Positions    1-200aa; Full Length
 Sequence    MAKKTYDLLF KLLLIGDSGV GKTCVLFRFS DDAFNTTFIS TIGIDFKIKT VELQGKKIKL QIWDTAGQER FHTITTSYYR GAMGIMLVYD ITNGKSFENI SKWLRNIDEH ANEDVERMLL GNKCDMDDKR VVPKGKGEQI AREHGIRFFE TSAKANINIE KAFLTLAEDI LRKTPVKEPN SENVDISSGG GVTGWKSKCC
 3D Structure    ModBase 3D Structure for P61027
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
 Production Note    Special Offer: The E. coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E. coli host-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E. coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E. coli host-expressed protein for the fastest delivery among all hosts. Please contact us or email to support@mybiosource.com for more details.
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Rab10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Rab10 recombinant protein

   The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, it regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response. Plays also a specific role in asymmetric protein transport to the plasma membrane within the polarized neuron and epithelial cells. In neurons, it is involved in axonogenesis through regulation of vesicular membrane trafficking toward the axonal plasma membrane while in epithelial cells, it regulates transport from the Golgi to the basolateral membrane. Moreover, may play a role in the basolateral recycling pathway and in phagosome maturation. Finally, may play a role in endoplasmic reticulum dynamics and morphology controlling tubulation along microtubules and tubules fusion.
 Product Categories/Family for Rab10 recombinant protein    Signal Transduction
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 SDS-Page of Rab10 recombinant protein    Rab10 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Rab10. It may not necessarily be applicable to this product.
 NCBI GI #    7710086
 NCBI GeneID    19325
 NCBI Accession #    NP_057885.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_016676.5 [Other Products]
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 UniProt Primary Accession #    P61027 [Other Products]
 UniProt Secondary Accession #    O88386; Q9D7X6 [Other Products]
 UniProt Related Accession #    P61027 [Other Products]
 Molecular Weight    22,541 Da
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 NCBI Official Full Name    ras-related protein Rab-10
 NCBI Official Synonym Full Names    RAB10, member RAS oncogene family
 NCBI Official Symbol    Rab10 [Similar Products]
 NCBI Official Synonym Symbols   
AW107754
[Similar Products]
 NCBI Protein Information    ras-related protein Rab-10
 UniProt Protein Name    Ras-related protein Rab-10
 Protein Family    Ras-related protein
 UniProt Gene Name    Rab10 [Similar Products]
 UniProt Entry Name    RAB10_MOUSE
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 UniProt Comments for Rab10    RAB10: a protein of the GTPase superfamily, Rab family. May be involved in vesicular trafficking and neurotransmitter release. Localized to the inner face of the cell membrane by a lipid-anchor.

Protein type: G protein, monomeric; G protein; G protein, monomeric, Rab

Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; focal adhesion; endoplasmic reticulum; cell; trans-Golgi network; recycling endosome; cell projection; membrane; perinuclear region of cytoplasm; plasma membrane; endosome membrane; cytoplasmic vesicle; intracellular; endosome

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; myosin V binding; nucleotide binding

Biological Process: metabolic process; establishment of neuroblast polarity; protein secretion; endosome transport; vesicle-mediated transport; regulation of exocytosis; antigen processing and presentation; intracellular protein transport; Golgi to plasma membrane transport; protein transport; axonogenesis; cellular response to insulin stimulus; transport; small GTPase mediated signal transduction; Rab protein signal transduction; vesicle docking during exocytosis
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 Research Articles on Rab10    1. RAB10 and its GTPase-activating protein AS160 comprise the principal signaling module downstream of insulin receptor activation that regulates the accumulation of GLUT4 transport vesicles at the plasma membrane.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Rab10 recombinant proteinPathways associated with Rab10 recombinant protein
 Reference Product  PubMed Publications
 Rims1 recombinant protein  >1 publications with Rab10 and Rims1
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Translocation Of GLUT4 To The Plasma Membrane Pathway antibodies  Translocation Of GLUT4 To The Plasma Membrane Pathway Diagram
Diseases associated with Rab10 recombinant proteinOrgans/Tissues associated with Rab10 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with Rab10 and Inflammation
 Carcinoma, Hepatocellular Antibodies  >1 publications with Rab10 and Carcinoma, Hepatocellular
 Weight Loss Antibodies  >1 publications with Rab10 and Weight Loss
 Liver Diseases Antibodies  >1 publications with Rab10 and Liver Diseases
 Ovarian Diseases Antibodies  >1 publications with Rab10 and Ovarian Diseases
 Edema Antibodies  >1 publications with Rab10 and Edema
 Fibrosis Antibodies  >1 publications with Rab10 and Fibrosis
 Disease Models, Animal Antibodies  >1 publications with Rab10 and Disease Models, Animal
 Liver Neoplasms Antibodies  >1 publications with Rab10 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >11 publications with Rab10 and Muscle
 Brain Antibodies  >9 publications with Rab10 and Brain
 Kidney Antibodies  >5 publications with Rab10 and Kidney
 Liver Antibodies  >4 publications with Rab10 and Liver
 Lung Antibodies  >2 publications with Rab10 and Lung
 Eye Antibodies  >2 publications with Rab10 and Eye
 Intestine Antibodies  >2 publications with Rab10 and Intestine
 Uterus Antibodies  >1 publications with Rab10 and Uterus
 Pancreas Antibodies  >1 publications with Rab10 and Pancreas
 Stomach Antibodies  >1 publications with Rab10 and Stomach
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