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RGMA recombinant protein :: Repulsive guidance molecule A (RGMA) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1351415 RGMA recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $660 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $885 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $945 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $975 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,070 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,180 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,185 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,210 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,375 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,715 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,795 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,840 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,285 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Repulsive guidance molecule A (RGMA), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Repulsive guidance molecule A (RGMA)

 Product Gene Name   

RGMA recombinant protein

[Similar Products]
 Product Synonym Gene Name    RGMA [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1351415 MSDS    MSDS PDF
 MBS1351415 Technical Datasheet    Technical Datasheet PDF
 Sequence Positions    169-424aa, Full Length of Mature Protein
 Sequence    PHLRTFTDRF QTCKVQGAWP LIDNNYLNVQ VTNTPVLPGS AATATSKLTI IFKNFQECVD QKVYQAEMDE LPAAFVDGSK NGGDKHGANS LKITEKVSGQ HVEIQAKYIG TTIVVRQVGR YLTFAVRMPE EVVNAVEDWD SQGLYLCLRG CPLNQQIDFQ AFHTNAEGTG ARRLAAASPA PTAPETFPYE TAVAKCKEKL PVEDLYYQAC VFDLLTTGDV NFTLAAYYAL EDVKMLHSNK DKLHLYDRTR DLPGRA
 OMIM    607362
 3D Structure    ModBase 3D Structure for Q96B86
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of RGMA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for RGMA recombinant protein

   This gene encodes a member of the repulsive guidance molecule family. The encoded protein is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. This protein may also function as a tumor suppressor in some cancers. Alternate splicing results in multiple transcript variants.
NCBI/Uniprot data below describe general gene information for RGMA. It may not necessarily be applicable to this product.
 NCBI GI #    261878463
 NCBI GeneID    56963
 NCBI Accession #    NP_001159755.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001166283.1 [Other Products]
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 UniProt Primary Accession #    Q96B86 [Other Products]
 UniProt Secondary Accession #    Q0JV97; Q8NC80; Q9H0E6; Q9NPM3; B2RTW1; B7Z5S8; F5GXQ7; F5GZU6; G3V518 [Other Products]
 UniProt Related Accession #    Q96B86 [Other Products]
 Molecular Weight    50,035 Da
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 NCBI Official Full Name    repulsive guidance molecule A isoform 1
 NCBI Official Synonym Full Names    repulsive guidance molecule BMP co-receptor a
 NCBI Official Symbol    RGMA [Similar Products]
 NCBI Official Synonym Symbols   
RGM
[Similar Products]
 NCBI Protein Information    repulsive guidance molecule A
 UniProt Protein Name    Repulsive guidance molecule A
 UniProt Synonym Protein Names   
RGM domain family member A
 Protein Family    Repulsive guidance molecule
 UniProt Gene Name    RGMA [Similar Products]
 UniProt Synonym Gene Names    RGM [Similar Products]
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 NCBI Summary for RGMA    This gene encodes a member of the repulsive guidance molecule family. The encoded protein is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. This protein may also function as a tumor suppressor in some cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
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 UniProt Comments for RGMA    Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway. It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.
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 Research Articles on RGMA    1. Dysregulation of RGMa plays an important role in the pathology of Parkinson's disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RGMA recombinant proteinPathways associated with RGMA recombinant protein
 Reference Product  PubMed Publications
 BMP2 recombinant protein  >5 publications with RGMA and BMP2
 BMPR2 recombinant protein  >4 publications with RGMA and BMPR2
 NEO1 recombinant protein  >3 publications with RGMA and NEO1
 BMP4 recombinant protein  >2 publications with RGMA and BMP4
 SMAD9 recombinant protein  >1 publications with RGMA and SMAD9
 SMAD5 recombinant protein  >1 publications with RGMA and SMAD5
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Netrin-1 Signaling Pathway antibodies  Netrin-1 Signaling Pathway Diagram
Diseases associated with RGMA recombinant proteinOrgans/Tissues associated with RGMA recombinant protein
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >3 publications with RGMA and Disease Models, Animal
 Neural Tube Defects Antibodies  >2 publications with RGMA and Neural Tube Defects
 Drug Toxicity Antibodies  >2 publications with RGMA and Drug Toxicity
 Prostatic Diseases Antibodies  >2 publications with RGMA and Prostatic Diseases
 Neoplasm Metastasis Antibodies  >2 publications with RGMA and Neoplasm Metastasis
 Necrosis Antibodies  >2 publications with RGMA and Necrosis
 Mood Disorders Antibodies  >1 publications with RGMA and Mood Disorders
 Arthritis, Experimental Antibodies  >1 publications with RGMA and Arthritis, Experimental
 Edema Antibodies  >1 publications with RGMA and Edema
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >30 publications with RGMA and Brain
 Embryonic Tissue Antibodies  >15 publications with RGMA and Embryonic Tissue
 Muscle Antibodies  >11 publications with RGMA and Muscle
 Eye Antibodies  >7 publications with RGMA and Eye
 Intestine Antibodies  >2 publications with RGMA and Intestine
 Lung Antibodies  >2 publications with RGMA and Lung
 Connective Tissue Antibodies  >2 publications with RGMA and Connective Tissue
 Mammary Gland Antibodies  >1 publications with RGMA and Mammary Gland
 Pancreas Antibodies  >1 publications with RGMA and Pancreas
 Ovary Antibodies  >1 publications with RGMA and Ovary
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