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ALDH1A2 recombinant protein :: Retinal dehydrogenase 2 (ALDH1A2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS7053455
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Retinal dehydrogenase 2 (ALDH1A2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Retinal dehydrogenase 2 (ALDH1A2)

 Product Gene Name   

ALDH1A2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-480aa, Full length of isoform 2
 Sequence    MTSSKIEMPG EVKADPAALM ASLHLLPSPT PNLEIKYTKI FINNEWQNSE SGRVFPVYNP ATGEQVCEVQ EADKADIDKA VQAARLAFSL GSVWRRMDAS ERGRLLDKLA DLVERDRAVL ATMESLNGGK PFLQAFYVDL QGVIKTFRYY AGWADKIHGM TIPVDGDYFT FTRHEPIGVC GQIIPWNFPL LMFAWKIAPA LCCGNTVVIK PAEQTPLSAL YMGALIKEVG KLIQEAAGRS NLKRVTLELG GKSPNIIFAD ADLDYAVEQA HQGVFFNQGQ CCTAGSRIFV EESIYEEFVR RSVERAKRRV VGSPFDPTTE QGPQIDKKQY NKILELIQSG VAEGAKLECG GKGLGRKGFF IEPTVFSNVT DDMRIAKEEI FGPVQEILRF KTMDEVIERA NNSDFGLVAA VFTNDINKAL TVSSAMQAGT VWINCYNALN AQSPFGGFKM SGNGREMGEF GLREYSEVKT VTVKIPQKNS
 OMIM    603687
 3D Structure    ModBase 3D Structure for O94788
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ALDH1A2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ALDH1A2 recombinant protein

   This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.
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 SDS-Page of ALDH1A2 recombinant protein    ALDH1A2 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for ALDH1A2. It may not necessarily be applicable to this product.
 NCBI GI #    332634711
 NCBI GeneID    8854
 NCBI Accession #    NP_001193826.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001206897.1 [Other Products]
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 UniProt Primary Accession #    O94788 [Other Products]
 UniProt Secondary Accession #    Q2PJS6; Q8NHQ4; Q9UBR8; Q9UFY0; B3KY52; B4DZR2; F5H2Y9; H0YM00 [Other Products]
 UniProt Related Accession #    O94788 [Other Products]
 Molecular Weight    46,137 Da
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 NCBI Official Full Name    retinal dehydrogenase 2 isoform 4
 NCBI Official Synonym Full Names    aldehyde dehydrogenase 1 family member A2
 NCBI Official Symbol    ALDH1A2 [Similar Products]
 NCBI Official Synonym Symbols   
RALDH2; RALDH2-T; RALDH(II)
[Similar Products]
 NCBI Protein Information    retinal dehydrogenase 2
 UniProt Protein Name    Retinal dehydrogenase 2
 UniProt Synonym Protein Names   
Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II)
 Protein Family    Retinal dehydrogenase
 UniProt Gene Name    ALDH1A2 [Similar Products]
 UniProt Synonym Gene Names    RALDH2; RALDH 2; RalDH2; RALDH(II) [Similar Products]
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 NCBI Summary for ALDH1A2    This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]
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 UniProt Comments for ALDH1A2    Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently ().
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 Research Articles on ALDH1A2    1. high transcription activities of ALDH1A2, ALDH1A3 and ALDH1L1 predicted worsen overall survival in gastric cancer patients
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ALDH1A2 recombinant proteinDiseases associated with ALDH1A2 recombinant protein
 Products by Pathway  Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
 Vitamin A And Carotenoid Metabolism Pathway antibodies  Vitamin A And Carotenoid Metabolism Pathway Diagram
 Retinoate Biosynthesis I Pathway antibodies  Retinoate Biosynthesis I Pathway Diagram
 Retinoate Biosynthesis I Pathway antibodies  Retinoate Biosynthesis I Pathway Diagram
 Disease Name  Pubmed Publications
 Drug Toxicity Antibodies  >4 publications with ALDH1A2 and Drug Toxicity
 Inflammation Antibodies  >4 publications with ALDH1A2 and Inflammation
 Nervous System Diseases Antibodies  >4 publications with ALDH1A2 and Nervous System Diseases
 Kidney Diseases Antibodies  >3 publications with ALDH1A2 and Kidney Diseases
 Prostatic Diseases Antibodies  >3 publications with ALDH1A2 and Prostatic Diseases
 Nervous System Malformations Antibodies  >3 publications with ALDH1A2 and Nervous System Malformations
 Heart Diseases Antibodies  >3 publications with ALDH1A2 and Heart Diseases
 Prostatic Neoplasms Antibodies  >3 publications with ALDH1A2 and Prostatic Neoplasms
 Disease Models, Animal Antibodies  >2 publications with ALDH1A2 and Disease Models, Animal
 Abnormalities, Drug-Induced Antibodies  >2 publications with ALDH1A2 and Abnormalities, Drug-Induced
Organs/Tissues associated with ALDH1A2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >15 publications with ALDH1A2 and Embryonic Tissue
 Blood Antibodies  >14 publications with ALDH1A2 and Blood
 Bone Antibodies  >13 publications with ALDH1A2 and Bone
 Brain Antibodies  >12 publications with ALDH1A2 and Brain
 Heart Antibodies  >9 publications with ALDH1A2 and Heart
 Eye Antibodies  >7 publications with ALDH1A2 and Eye
 Lung Antibodies  >7 publications with ALDH1A2 and Lung
 Intestine Antibodies  >7 publications with ALDH1A2 and Intestine
 Kidney Antibodies  >6 publications with ALDH1A2 and Kidney
 Bone Marrow Antibodies  >6 publications with ALDH1A2 and Bone Marrow
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