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RDH12 recombinant protein :: Retinol dehydrogenase 12 (RDH12) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS959514 RDH12 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $725 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $975 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $990 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,065 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,140 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,230 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,245 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,290 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,515 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,795 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,865 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,960 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,390 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Retinol dehydrogenase 12 (RDH12), Recombinant Protein

 Also Known As   

Recombinant Bovine Retinol dehydrogenase 12 (RDH12)

 Product Gene Name   

RDH12 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-316aa, Full length protein
 Sequence    MLVVLGLLTS FLSFLYVIAP SIRKFFAGGV CRTDVQLFGK VVVITGANTG IGKETARELA RRGARVYIAC RDVLKGESAA SEIQADTKNS QVLVRKLDLS DTKSIRAFAE GFLAEEKQLH ILINNAGVML CPYSKTADGF ETHLAVNHLG HFLLTHLLLG RLKESAPARV VNLSSVAHHL GKIRFHDLQG DKYYNLGFAY CHSKLANVLF TRELAKRLKG TGVTTYAVHP GIVRSKLVRH SFLLCLLWRL FSPFLKTTWE GAQTSLHCAL AEGLEPLSGK YFSDCKKTWV SPRARNNKTA ERLWNVSCEL LGIRWE
 3D Structure    ModBase 3D Structure for P59837
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Bovine
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of RDH12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for RDH12 recombinant protein

   This protein is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
NCBI/Uniprot data below describe general gene information for RDH12. It may not necessarily be applicable to this product.
 NCBI GI #    34365787
 NCBI GeneID    369021
 NCBI Accession #    NP_899207.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_183363.1 [Other Products]
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 UniProt Primary Accession #    P59837 [Other Products]
 UniProt Related Accession #    P59837 [Other Products]
 Molecular Weight    35,171 Da
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 NCBI Official Full Name    retinol dehydrogenase 12
 NCBI Official Synonym Full Names    retinol dehydrogenase 12
 NCBI Official Symbol    RDH12 [Similar Products]
 NCBI Official Synonym Symbols   
DSSDR2
[Similar Products]
 NCBI Protein Information    retinol dehydrogenase 12
 UniProt Protein Name    Retinol dehydrogenase 12
 UniProt Synonym Protein Names   
Double substrate specificity short-chain dehydrogenase/reductase 2
 Protein Family    Retinol dehydrogenase
 UniProt Gene Name    RDH12 [Similar Products]
 UniProt Synonym Gene Names    DSSDR2 [Similar Products]
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 UniProt Comments for RDH12    Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments ().
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with RDH12 recombinant proteinDiseases associated with RDH12 recombinant protein
 Products by Pathway  Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Eye Diseases Antibodies  >35 publications with RDH12 and Eye Diseases
 Retinal Degeneration Antibodies  >32 publications with RDH12 and Retinal Degeneration
 Leber Congenital Amaurosis Antibodies  >27 publications with RDH12 and Leber Congenital Amaurosis
 Eye Diseases, Hereditary Antibodies  >17 publications with RDH12 and Eye Diseases, Hereditary
 Vision Disorders Antibodies  >16 publications with RDH12 and Vision Disorders
 Retinitis Pigmentosa Antibodies  >12 publications with RDH12 and Retinitis Pigmentosa
 Retinal Dystrophies Antibodies  >8 publications with RDH12 and Retinal Dystrophies
 Macular Degeneration Antibodies  >3 publications with RDH12 and Macular Degeneration
 Amblyopia Antibodies  >2 publications with RDH12 and Amblyopia
 Obesity Antibodies  >1 publications with RDH12 and Obesity
Organs/Tissues associated with RDH12 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with RDH12 and Brain
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