NP_001027984.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
cathepsin K
NCBI Protein Information
cathepsin K; cathepsin K preproprotein
UniProt Protein Name
Cathepsin K
UniProt Entry Name
CATK_MACMU
UniProt Comments for CTSK
Function: Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation
By similarity.
Catalytic activity: Broad proteolytic activity. With small-molecule substrates and inhibitors, the major determinant of specificity is P2, which is preferably Leu, Met > Phe, and not Arg.
Subcellular location: Lysosome
By similarity.
Sequence similarities: Belongs to the peptidase C1 family.
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Pathways associated with CTSK recombinant protein
Diseases associated with CTSK recombinant protein
Organs/Tissues associated with CTSK recombinant protein
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