XP_002803395.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
cytochrome c-like
NCBI Protein Information
cytochrome c, somatic
UniProt Protein Name
Cytochrome c
UniProt Synonym Gene Names
UniProt Entry Name
CYC_MACMU
UniProt Comments for CYCS
Function: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases
By similarity.
Subcellular location: Mitochondrion intermembrane space. Note: Loosely associated with the inner membrane.
Post-translational modification: Binds 1 heme group per subunit.Phosphorylation at Tyr-49 and Tyr-98 both reduce by half the turnover in the reaction with cytochrome c oxidase, down-regulating mitochondrial respiration
By similarity.
Sequence similarities: Belongs to the cytochrome c family.
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Pathways associated with CYCS recombinant protein
Diseases associated with CYCS recombinant protein
Organs/Tissues associated with CYCS recombinant protein
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