NP_001073588.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
growth/differentiation factor 8
NCBI Official Synonym Symbols
NCBI Protein Information
growth/differentiation factor 8; GDF-8
UniProt Protein Name
Growth/differentiation factor 8
UniProt Synonym Protein Names
Myostatin
UniProt Synonym Gene Names
UniProt Entry Name
GDF8_MACMU
UniProt Comments for MSTN
Function: Acts specifically as a negative regulator of skeletal muscle growth
By similarity.
Subunit structure: Homodimer; disulfide-linked
By similarity. Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FST3
By similarity.
Subcellular location: Secreted
By similarity.
Sequence similarities: Belongs to the TGF-beta family.
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Diseases associated with MSTN recombinant protein
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