NP_001073161.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Related Accession #
NCBI Official Full Name
interferon-induced GTP-binding protein Mx1
NCBI Protein Information
interferon-induced GTP-binding protein Mx1; myxoma resistance protein 1; myxovirus resistance protein 1
UniProt Protein Name
Interferon-induced GTP-binding protein Mx1
UniProt Synonym Protein Names
Myxoma resistance protein 1; Myxovirus resistance protein 1
UniProt Entry Name
MX1_MACMU
UniProt Comments for MX1
Function: Dynamin-like GTPase acting as a cell-autonomous host restriction factor against many viral pathogens
By similarity.May regulate the calcium channel activity of TRPCs. Ring-like assemblies may induce membrane tubulation
By similarity.
Subunit structure: Oligomerizes (via the stalk domain) in a criss-cross pattern to form a linear stalk filament, may form ring-like structures with a 24 Angstrom inner diameter. Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7
By similarity.
Subcellular location: Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side
By similarity. Note: Binds preferentially to negatively charged phospholipids
By similarity.
Induction: By type I and type III interferons.
Sequence similarities: Belongs to the dynamin family.Contains 1 GED domain.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with MX1 recombinant protein
Diseases associated with MX1 recombinant protein
Organs/Tissues associated with MX1 recombinant protein
|